TY - JOUR T1 - Keratoacanthoma developing in sites of previous trauma: a report of two cases and review of the literature. AU - Pattee,Sean F, AU - Silvis,Nancy G, PY - 2003/2/13/pubmed PY - 2003/5/8/medline PY - 2003/2/13/entrez SP - S35 EP - 8 JF - Journal of the American Academy of Dermatology JO - J Am Acad Dermatol VL - 48 IS - 2 Suppl N2 - Keratoacanthoma is a common benign squamous neoplasm that only rarely progresses to metastatic carcinoma. The cause of keratoacanthoma is unclear; however, suspected causes include ultraviolet light, genetic factors, immunosuppression, chemical carcinogens, viruses, and trauma. Keratoacanthomas have been reported only rarely to arise in sites of previous trauma. We report 2 cases of keratoacanthomas arising shortly after episodes of cutaneous trauma and provide a review of the literature of similar cases previously reported. It is likely that an interaction exists between a variety of factors in the development of keratoacanthomas; however, it appears that a predilection exists for these lesions to arise in trauma sites. SN - 0190-9622 UR - https://www.unboundmedicine.com/medline/citation/12582383/Keratoacanthoma_developing_in_sites_of_previous_trauma:_a_report_of_two_cases_and_review_of_the_literature_ DB - PRIME DP - Unbound Medicine ER -