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Response of liver antioxidant system to taurine in rats fed high fructose diet.
Indian J Exp Biol 2002; 40(9):1016-9IJ

Abstract

Fructose-fed rats were more susceptible to peroxidative damage as measured by thiobarbituric acid reactive species. The concentrations of lipid peroxides, diene conjugates, lipofuscin and hydroperoxides were significantly higher. The levels of enzymic antioxidants such as vitamin C, vitamin E and glutathione and activities of antioxidant enzymes were significantly lower in fructose-fed rats. When these rats received taurine in drinking water, peroxidative damage was minimal in both plasma and liver. Taurine was effective in inducing the antioxidant potential in fructose-fed rats. Increased peroxidative damage in liver is likely to be associated with fructose dependent pathology, which could be reduced by taurine by enhancing the antioxidant potential.

Authors+Show Affiliations

Department of Biochemistry, Faculty of Science, Annamalai University, Annamalainagar 608 002, India.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12587730

Citation

Nandhini, A T Anitha, et al. "Response of Liver Antioxidant System to Taurine in Rats Fed High Fructose Diet." Indian Journal of Experimental Biology, vol. 40, no. 9, 2002, pp. 1016-9.
Nandhini AT, Balakrishnan SD, Anuradha CV. Response of liver antioxidant system to taurine in rats fed high fructose diet. Indian J Exp Biol. 2002;40(9):1016-9.
Nandhini, A. T., Balakrishnan, S. D., & Anuradha, C. V. (2002). Response of liver antioxidant system to taurine in rats fed high fructose diet. Indian Journal of Experimental Biology, 40(9), pp. 1016-9.
Nandhini AT, Balakrishnan SD, Anuradha CV. Response of Liver Antioxidant System to Taurine in Rats Fed High Fructose Diet. Indian J Exp Biol. 2002;40(9):1016-9. PubMed PMID: 12587730.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Response of liver antioxidant system to taurine in rats fed high fructose diet. AU - Nandhini,A T Anitha, AU - Balakrishnan,S D, AU - Anuradha,C V, PY - 2003/2/18/pubmed PY - 2003/4/12/medline PY - 2003/2/18/entrez SP - 1016 EP - 9 JF - Indian journal of experimental biology JO - Indian J. Exp. Biol. VL - 40 IS - 9 N2 - Fructose-fed rats were more susceptible to peroxidative damage as measured by thiobarbituric acid reactive species. The concentrations of lipid peroxides, diene conjugates, lipofuscin and hydroperoxides were significantly higher. The levels of enzymic antioxidants such as vitamin C, vitamin E and glutathione and activities of antioxidant enzymes were significantly lower in fructose-fed rats. When these rats received taurine in drinking water, peroxidative damage was minimal in both plasma and liver. Taurine was effective in inducing the antioxidant potential in fructose-fed rats. Increased peroxidative damage in liver is likely to be associated with fructose dependent pathology, which could be reduced by taurine by enhancing the antioxidant potential. SN - 0019-5189 UR - https://www.unboundmedicine.com/medline/citation/12587730/Response_of_liver_antioxidant_system_to_taurine_in_rats_fed_high_fructose_diet_ L2 - https://medlineplus.gov/antioxidants.html DB - PRIME DP - Unbound Medicine ER -