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Microbiological aspects of diaper dermatitis.
Dermatology. 2003; 206(2):136-41.D

Abstract

BACKGROUND

The microbiological basis of diaper dermatitis is not clearly elucidated, although a better knowledge of microbial colonisation can be of importance with regard to an adequate treatment.

OBJECTIVE

To investigate the relevance of candida sp. and Staphylococcus aureus colonisation in diaper dermatitis and to determine the correlation between the extent of colonisation and the severity of disease.

METHODS

Growth of candida sp. and S. aureus in the perianal, inguinal and oral regions was determined by positive/negative and semi-quantitative analysis in an open, multi-centre (n = 3) study. Forty-eight children with healthy skin and 28 with diaper dermatitis were analysed. The severity of diaper dermatitis was assessed using a total symptoms score.

RESULTS

Colonisation by candida sp. was significantly more frequent in children with diaper dermatitis as compared to those with healthy skin (perianal 75 vs. 19%; inguinal 50 vs. 10%; oral 68 vs. 25%, p < 0.0003), whereas colonisation by S. aureus at the 3 swab locations was not different (p > 0.34). There was a highly significant, positive correlation between severity of disease and extent of candida sp. colonisation at all swab locations.

CONCLUSIONS

Limited microbial colonisation in diaper dermatitis is of questionable relevance, but extensive colonisation seems to aggravate the symptoms; therefore, we suggest that semi-quantitative evaluation should be preferred to the positive/negative assessment for a differential diagnosis.

Authors+Show Affiliations

Paediatric practice, Zurich, Switzerland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study

Language

eng

PubMed ID

12592081

Citation

Ferrazzini, G, et al. "Microbiological Aspects of Diaper Dermatitis." Dermatology (Basel, Switzerland), vol. 206, no. 2, 2003, pp. 136-41.
Ferrazzini G, Kaiser RR, Hirsig Cheng SK, et al. Microbiological aspects of diaper dermatitis. Dermatology. 2003;206(2):136-41.
Ferrazzini, G., Kaiser, R. R., Hirsig Cheng, S. K., Wehrli, M., Della Casa, V., Pohlig, G., Gonser, S., Graf, F., & Jörg, W. (2003). Microbiological aspects of diaper dermatitis. Dermatology (Basel, Switzerland), 206(2), 136-41.
Ferrazzini G, et al. Microbiological Aspects of Diaper Dermatitis. Dermatology. 2003;206(2):136-41. PubMed PMID: 12592081.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Microbiological aspects of diaper dermatitis. AU - Ferrazzini,G, AU - Kaiser,R R, AU - Hirsig Cheng,S-K, AU - Wehrli,M, AU - Della Casa,V, AU - Pohlig,G, AU - Gonser,S, AU - Graf,F, AU - Jörg,W, PY - 2002/04/02/received PY - 2002/07/25/accepted PY - 2003/2/20/pubmed PY - 2003/6/5/medline PY - 2003/2/20/entrez SP - 136 EP - 41 JF - Dermatology (Basel, Switzerland) JO - Dermatology VL - 206 IS - 2 N2 - BACKGROUND: The microbiological basis of diaper dermatitis is not clearly elucidated, although a better knowledge of microbial colonisation can be of importance with regard to an adequate treatment. OBJECTIVE: To investigate the relevance of candida sp. and Staphylococcus aureus colonisation in diaper dermatitis and to determine the correlation between the extent of colonisation and the severity of disease. METHODS: Growth of candida sp. and S. aureus in the perianal, inguinal and oral regions was determined by positive/negative and semi-quantitative analysis in an open, multi-centre (n = 3) study. Forty-eight children with healthy skin and 28 with diaper dermatitis were analysed. The severity of diaper dermatitis was assessed using a total symptoms score. RESULTS: Colonisation by candida sp. was significantly more frequent in children with diaper dermatitis as compared to those with healthy skin (perianal 75 vs. 19%; inguinal 50 vs. 10%; oral 68 vs. 25%, p < 0.0003), whereas colonisation by S. aureus at the 3 swab locations was not different (p > 0.34). There was a highly significant, positive correlation between severity of disease and extent of candida sp. colonisation at all swab locations. CONCLUSIONS: Limited microbial colonisation in diaper dermatitis is of questionable relevance, but extensive colonisation seems to aggravate the symptoms; therefore, we suggest that semi-quantitative evaluation should be preferred to the positive/negative assessment for a differential diagnosis. SN - 1018-8665 UR - https://www.unboundmedicine.com/medline/citation/12592081/Microbiological_aspects_of_diaper_dermatitis_ DB - PRIME DP - Unbound Medicine ER -