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[Review of studies on exposure to aluminum and Alzheimer's disease].
Rev Esp Salud Publica. 2002 Nov-Dec; 76(6):645-58.RE

Abstract

A review has been made of the epidemiological studies published evaluating the role of aluminum as a risk factor for developing Alzheimer's disease. A search for published studies was conducted in the Medline database by combining the terms "Aluminum" and "Alzheimer's disease". In most of the studies reviewed, exposure to aluminum in drinking water was examined. These studies suggest that a relationship exists between aluminum (Al) and Alzheimer's disease involving relative risks of around 2 for populations exposed to Al concentrations in drinking water higher than 0.1 mg/l. Types of exposure to this metal by other means (food, medications and occupational exposure) have received little attention. These epidemiological studies entail certain methodological limitations, and their results are not consistent, so the results available to date therefore not making it possible to clearly determine that any relationship exists between exposure to aluminum and the etiology of Alzheimer's disease. Nevertheless, the toxic effect of aluminum on human health cannot be ruled out either, and thus exposure to aluminum should be monitored and limited as far as possible.

Authors+Show Affiliations

Escola Valenciana d'Estudis per a la Salut (EVES), Unidad de Epidemiología y Estadística, C/Juan de Garay 21 46017 Valencia.No affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Review

Language

spa

PubMed ID

12602134

Citation

Suay Llopis, Loreto, and Ferran Ballester Díez. "[Review of Studies On Exposure to Aluminum and Alzheimer's Disease]." Revista Espanola De Salud Publica, vol. 76, no. 6, 2002, pp. 645-58.
Suay Llopis L, Ballester Díez F. [Review of studies on exposure to aluminum and Alzheimer's disease]. Rev Esp Salud Publica. 2002;76(6):645-58.
Suay Llopis, L., & Ballester Díez, F. (2002). [Review of studies on exposure to aluminum and Alzheimer's disease]. Revista Espanola De Salud Publica, 76(6), 645-58.
Suay Llopis L, Ballester Díez F. [Review of Studies On Exposure to Aluminum and Alzheimer's Disease]. Rev Esp Salud Publica. 2002 Nov-Dec;76(6):645-58. PubMed PMID: 12602134.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Review of studies on exposure to aluminum and Alzheimer's disease]. AU - Suay Llopis,Loreto, AU - Ballester Díez,Ferran, PY - 2003/2/27/pubmed PY - 2003/3/26/medline PY - 2003/2/27/entrez SP - 645 EP - 58 JF - Revista espanola de salud publica JO - Rev Esp Salud Publica VL - 76 IS - 6 N2 - A review has been made of the epidemiological studies published evaluating the role of aluminum as a risk factor for developing Alzheimer's disease. A search for published studies was conducted in the Medline database by combining the terms "Aluminum" and "Alzheimer's disease". In most of the studies reviewed, exposure to aluminum in drinking water was examined. These studies suggest that a relationship exists between aluminum (Al) and Alzheimer's disease involving relative risks of around 2 for populations exposed to Al concentrations in drinking water higher than 0.1 mg/l. Types of exposure to this metal by other means (food, medications and occupational exposure) have received little attention. These epidemiological studies entail certain methodological limitations, and their results are not consistent, so the results available to date therefore not making it possible to clearly determine that any relationship exists between exposure to aluminum and the etiology of Alzheimer's disease. Nevertheless, the toxic effect of aluminum on human health cannot be ruled out either, and thus exposure to aluminum should be monitored and limited as far as possible. SN - 1135-5727 UR - https://www.unboundmedicine.com/medline/citation/12602134/[Review_of_studies_on_exposure_to_aluminum_and_Alzheimer's_disease]_ L2 - https://www.mscbs.gob.es/biblioPublic/publicaciones/recursos_propios/resp/revista_cdrom/vol76/vol76_6/RS766C_645.pdf DB - PRIME DP - Unbound Medicine ER -