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Efficacy of Crotalidae polyvalent antivenin for the treatment of hognosed viper (Porthidium nasutum) envenomation.
Ann Emerg Med. 2003 Mar; 41(3):391-5.AE

Abstract

Envenomation from pit vipers native to North America can be treated successfully with either of the 2 commercially available antivenoms licensed in the United States. However, envenomations from imported snakes held in zoos or private collections often pose unique challenges to management because of the lack of specific antivenom and the unclear efficacy of the available licensed products. We report the case of a 37-year-old man who was envenomated on his left hand by his pet hognosed viper (Porthidium nasutum). He had swelling at the wound site that progressively worsened over 3 to 4 hours. His symptom progression included the structural motor impairment of his fingers and a sensory deficit. Treatment with 8 vials of Antivenin (Crotalidae) polyvalent was associated with a halt of extremity swelling and restoration of neurologic and motor function of his hand. Limited experimental evidence provides support for antigenic cross-reactivity between Antivenin (Crotalidae) polyvalent and P nasutum venom.

Authors+Show Affiliations

New York City Poison Control Center, 455 First Avenue, Room 123, New York, NY 10016, USA. jschier@pol.netNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

12605207

Citation

Schier, Joshua G., et al. "Efficacy of Crotalidae Polyvalent Antivenin for the Treatment of Hognosed Viper (Porthidium Nasutum) Envenomation." Annals of Emergency Medicine, vol. 41, no. 3, 2003, pp. 391-5.
Schier JG, Wiener SW, Touger M, et al. Efficacy of Crotalidae polyvalent antivenin for the treatment of hognosed viper (Porthidium nasutum) envenomation. Ann Emerg Med. 2003;41(3):391-5.
Schier, J. G., Wiener, S. W., Touger, M., Nelson, L. S., & Hoffman, R. S. (2003). Efficacy of Crotalidae polyvalent antivenin for the treatment of hognosed viper (Porthidium nasutum) envenomation. Annals of Emergency Medicine, 41(3), 391-5.
Schier JG, et al. Efficacy of Crotalidae Polyvalent Antivenin for the Treatment of Hognosed Viper (Porthidium Nasutum) Envenomation. Ann Emerg Med. 2003;41(3):391-5. PubMed PMID: 12605207.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of Crotalidae polyvalent antivenin for the treatment of hognosed viper (Porthidium nasutum) envenomation. AU - Schier,Joshua G, AU - Wiener,Sage W, AU - Touger,Michael, AU - Nelson,Lewis S, AU - Hoffman,Robert S, PY - 2003/2/28/pubmed PY - 2003/4/1/medline PY - 2003/2/28/entrez SP - 391 EP - 5 JF - Annals of emergency medicine JO - Ann Emerg Med VL - 41 IS - 3 N2 - Envenomation from pit vipers native to North America can be treated successfully with either of the 2 commercially available antivenoms licensed in the United States. However, envenomations from imported snakes held in zoos or private collections often pose unique challenges to management because of the lack of specific antivenom and the unclear efficacy of the available licensed products. We report the case of a 37-year-old man who was envenomated on his left hand by his pet hognosed viper (Porthidium nasutum). He had swelling at the wound site that progressively worsened over 3 to 4 hours. His symptom progression included the structural motor impairment of his fingers and a sensory deficit. Treatment with 8 vials of Antivenin (Crotalidae) polyvalent was associated with a halt of extremity swelling and restoration of neurologic and motor function of his hand. Limited experimental evidence provides support for antigenic cross-reactivity between Antivenin (Crotalidae) polyvalent and P nasutum venom. SN - 0196-0644 UR - https://www.unboundmedicine.com/medline/citation/12605207/Efficacy_of_Crotalidae_polyvalent_antivenin_for_the_treatment_of_hognosed_viper__Porthidium_nasutum__envenomation_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0196064402849125 DB - PRIME DP - Unbound Medicine ER -