Tags

Type your tag names separated by a space and hit enter

New oplopane and eremophilane derivatives from Robinsonecio gerberifolius.
J Nat Prod. 2003 Feb; 66(2):225-9.JN

Abstract

A phytochemical study of Robinsonecio gerberifolius afforded six new sesquiterpenoids, two oplopane (1and 2) and four eremophilane derivatives (3-6). The structures of these compounds were elucidated on spectroscopic grounds, and the absolute configurations of compounds 3 and 4 were established from CD analysis. The known 3beta-angeloyloxy-1,10-epoxyfuranoeremophilane (7) was also isolated, and its stereochemistry was revised. The cytotoxic activities of compounds 1-7 were determined against five human cancer cell lines.

Authors+Show Affiliations

Arciniegas A
Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Coyoacán 04510, D.F., México.
Pérez-Castorena AL
No affiliation info available
Reyes S
No affiliation info available
Contreras JL
No affiliation info available
De Vivar AR
No affiliation info available

MeSH

Antineoplastic Agents, PhytogenicAsteraceaeDrug Screening Assays, AntitumorHumansInhibitory Concentration 50MexicoMolecular ConformationMolecular StructureNuclear Magnetic Resonance, BiomolecularPlants, MedicinalSesquiterpenesStereoisomerismTumor Cells, CulturedX-Ray Diffraction

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12608854

Citation

Arciniegas, Amira, et al. "New Oplopane and Eremophilane Derivatives From Robinsonecio Gerberifolius." Journal of Natural Products, vol. 66, no. 2, 2003, pp. 225-9.
Arciniegas A, Pérez-Castorena AL, Reyes S, et al. New oplopane and eremophilane derivatives from Robinsonecio gerberifolius. J Nat Prod. 2003;66(2):225-9.
Arciniegas, A., Pérez-Castorena, A. L., Reyes, S., Contreras, J. L., & De Vivar, A. R. (2003). New oplopane and eremophilane derivatives from Robinsonecio gerberifolius. Journal of Natural Products, 66(2), 225-9.
Arciniegas A, et al. New Oplopane and Eremophilane Derivatives From Robinsonecio Gerberifolius. J Nat Prod. 2003;66(2):225-9. PubMed PMID: 12608854.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New oplopane and eremophilane derivatives from Robinsonecio gerberifolius. AU - Arciniegas,Amira, AU - Pérez-Castorena,Ana-L, AU - Reyes,Sibet, AU - Contreras,José Luis, AU - De Vivar,Alfonso Romo, PY - 2003/3/1/pubmed PY - 2003/7/8/medline PY - 2003/3/1/entrez SP - 225 EP - 9 JF - Journal of natural products JO - J Nat Prod VL - 66 IS - 2 N2 - A phytochemical study of Robinsonecio gerberifolius afforded six new sesquiterpenoids, two oplopane (1and 2) and four eremophilane derivatives (3-6). The structures of these compounds were elucidated on spectroscopic grounds, and the absolute configurations of compounds 3 and 4 were established from CD analysis. The known 3beta-angeloyloxy-1,10-epoxyfuranoeremophilane (7) was also isolated, and its stereochemistry was revised. The cytotoxic activities of compounds 1-7 were determined against five human cancer cell lines. SN - 0163-3864 UR - https://www.unboundmedicine.com/medline/citation/12608854/New_oplopane_and_eremophilane_derivatives_from_Robinsonecio_gerberifolius_ DB - PRIME DP - Unbound Medicine ER -