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Three cycloartane glycosides from Cimicifuga rhizome and their immunosuppressive activities in mouse allogeneic mixed lymphocyte reaction.
Chem Pharm Bull (Tokyo). 2003 Mar; 51(3):354-6.CP

Abstract

One known (1) and two new cycloartane triglycosides, 20S,22R,23S,24R-16beta,23;22,25-diepoxy-cycloartane-3beta,23,24-triol 3-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->2)-beta-D-xylopyranoside (2) and 20S,22R,23S,24R-16beta,23;22,25-diepoxy-cycloartane-3beta,23,24-triol 3-O-(6-O-trans-isoferuloyl-beta-D-glucopyranosyl)-(1-->2)-beta-D-glucopyranosyl-(1-->2)-beta-D-xylopyranoside (3), were isolated from a commercial Cimicifuga Rhizome. Their structures were determined by two dimensional (2D) NMR spectroscopic analysis and chemical evidence. These compounds suppressed the proliferation of lymphocytes in mouse allogeneic mixed lymphocyte reaction.

Authors+Show Affiliations

Faculty of Engineering, Kyushu Kyoritsu University, Kitakyushu, Japan.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12612431

Citation

Nishida, Makiko, et al. "Three Cycloartane Glycosides From Cimicifuga Rhizome and Their Immunosuppressive Activities in Mouse Allogeneic Mixed Lymphocyte Reaction." Chemical & Pharmaceutical Bulletin, vol. 51, no. 3, 2003, pp. 354-6.
Nishida M, Yoshimitsu H, Nohara T. Three cycloartane glycosides from Cimicifuga rhizome and their immunosuppressive activities in mouse allogeneic mixed lymphocyte reaction. Chem Pharm Bull (Tokyo). 2003;51(3):354-6.
Nishida, M., Yoshimitsu, H., & Nohara, T. (2003). Three cycloartane glycosides from Cimicifuga rhizome and their immunosuppressive activities in mouse allogeneic mixed lymphocyte reaction. Chemical & Pharmaceutical Bulletin, 51(3), 354-6.
Nishida M, Yoshimitsu H, Nohara T. Three Cycloartane Glycosides From Cimicifuga Rhizome and Their Immunosuppressive Activities in Mouse Allogeneic Mixed Lymphocyte Reaction. Chem Pharm Bull (Tokyo). 2003;51(3):354-6. PubMed PMID: 12612431.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Three cycloartane glycosides from Cimicifuga rhizome and their immunosuppressive activities in mouse allogeneic mixed lymphocyte reaction. AU - Nishida,Makiko, AU - Yoshimitsu,Hitoshi, AU - Nohara,Toshihiro, PY - 2003/3/4/pubmed PY - 2003/10/22/medline PY - 2003/3/4/entrez SP - 354 EP - 6 JF - Chemical & pharmaceutical bulletin JO - Chem Pharm Bull (Tokyo) VL - 51 IS - 3 N2 - One known (1) and two new cycloartane triglycosides, 20S,22R,23S,24R-16beta,23;22,25-diepoxy-cycloartane-3beta,23,24-triol 3-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->2)-beta-D-xylopyranoside (2) and 20S,22R,23S,24R-16beta,23;22,25-diepoxy-cycloartane-3beta,23,24-triol 3-O-(6-O-trans-isoferuloyl-beta-D-glucopyranosyl)-(1-->2)-beta-D-glucopyranosyl-(1-->2)-beta-D-xylopyranoside (3), were isolated from a commercial Cimicifuga Rhizome. Their structures were determined by two dimensional (2D) NMR spectroscopic analysis and chemical evidence. These compounds suppressed the proliferation of lymphocytes in mouse allogeneic mixed lymphocyte reaction. SN - 0009-2363 UR - https://www.unboundmedicine.com/medline/citation/12612431/Three_cycloartane_glycosides_from_Cimicifuga_rhizome_and_their_immunosuppressive_activities_in_mouse_allogeneic_mixed_lymphocyte_reaction_ L2 - https://joi.jlc.jst.go.jp/JST.JSTAGE/cpb/51.354?from=PubMed DB - PRIME DP - Unbound Medicine ER -