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Herpes zoster virus sclerokeratitis and anterior uveitis in a child following varicella vaccination.
Am J Ophthalmol. 2003 Mar; 135(3):415-7.AJ

Abstract

PURPOSE

To report a case of herpes zoster virus sclerokeratitis with anterior uveitis following vaccination with live attenuated varicella vaccine (Oka strain).

DESIGN

Case report.

METHODS

The case records of the patient were reviewed retrospectively. Pertinent literature citations were identified using MEDLINE.

RESULTS

A 9-year-old boy presented with herpes zoster ophthalmicus 3 years following vaccination with live attenuated varicella vaccine (Oka strain). Examination of the affected eye revealed a moderate follicular response on the palpebral conjunctiva, decreased corneal sensation, mildly elevated intraocular pressure, diffuse anterior scleritis with marginal keratitis, and a moderately severe anterior uveitis. Amplified DNA from fluid taken from the base of a cutaneous vesicle produced wild-type varicella zoster virus (VZV) DNA, not Oka strain.

CONCLUSIONS

Herpes zoster virus infection needs to be considered in all patients who present with scleritis, keratitis, or anterior uveitis, regardless of their varicella vaccination status.

Authors+Show Affiliations

Francis I. Proctor Foundation and Department of Ophthalmology, University of California at San Francisco Medical Center, San Francisco, California, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

12614776

Citation

Naseri, Ayman, et al. "Herpes Zoster Virus Sclerokeratitis and Anterior Uveitis in a Child Following Varicella Vaccination." American Journal of Ophthalmology, vol. 135, no. 3, 2003, pp. 415-7.
Naseri A, Good WV, Cunningham ET. Herpes zoster virus sclerokeratitis and anterior uveitis in a child following varicella vaccination. Am J Ophthalmol. 2003;135(3):415-7.
Naseri, A., Good, W. V., & Cunningham, E. T. (2003). Herpes zoster virus sclerokeratitis and anterior uveitis in a child following varicella vaccination. American Journal of Ophthalmology, 135(3), 415-7.
Naseri A, Good WV, Cunningham ET. Herpes Zoster Virus Sclerokeratitis and Anterior Uveitis in a Child Following Varicella Vaccination. Am J Ophthalmol. 2003;135(3):415-7. PubMed PMID: 12614776.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Herpes zoster virus sclerokeratitis and anterior uveitis in a child following varicella vaccination. AU - Naseri,Ayman, AU - Good,William V, AU - Cunningham,Emmett T,Jr PY - 2003/3/5/pubmed PY - 2003/3/18/medline PY - 2003/3/5/entrez SP - 415 EP - 7 JF - American journal of ophthalmology JO - Am. J. Ophthalmol. VL - 135 IS - 3 N2 - PURPOSE: To report a case of herpes zoster virus sclerokeratitis with anterior uveitis following vaccination with live attenuated varicella vaccine (Oka strain). DESIGN: Case report. METHODS: The case records of the patient were reviewed retrospectively. Pertinent literature citations were identified using MEDLINE. RESULTS: A 9-year-old boy presented with herpes zoster ophthalmicus 3 years following vaccination with live attenuated varicella vaccine (Oka strain). Examination of the affected eye revealed a moderate follicular response on the palpebral conjunctiva, decreased corneal sensation, mildly elevated intraocular pressure, diffuse anterior scleritis with marginal keratitis, and a moderately severe anterior uveitis. Amplified DNA from fluid taken from the base of a cutaneous vesicle produced wild-type varicella zoster virus (VZV) DNA, not Oka strain. CONCLUSIONS: Herpes zoster virus infection needs to be considered in all patients who present with scleritis, keratitis, or anterior uveitis, regardless of their varicella vaccination status. SN - 0002-9394 UR - https://www.unboundmedicine.com/medline/citation/12614776/Herpes_zoster_virus_sclerokeratitis_and_anterior_uveitis_in_a_child_following_varicella_vaccination_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002939402019578 DB - PRIME DP - Unbound Medicine ER -