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Preventive effects of Cassia auriculata L. flowers on brain lipid peroxidation in rats treated with streptozotocin.
Mol Cell Biochem. 2003 Jan; 243(1-2):23-8.MC

Abstract

The effect of aqueous extract of the flowers of Cassia auriculata were examined on antioxidants and lipid peroxidation in the brain of streptozotocin diabetic rats. Significant increase in the activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase and reduced glutathione were observed in brain on treatment with Cassia auriculata flower extract (CFEt) and glibenclamide. Both the treated groups showed significant decrease in thiobarbituric reactive substances (TBARS) and hydroperoxide formation in brain, suggesting its role in protection against lipid peroxidation induced membrane damage. Since the study of induction of the antioxidant enzymes is considered to be a reliable marker for evaluating the antiperoxidative efficacy of medicinal plant, these findings are suggestions of possible antiperoxidative role played by Cassia auriculata flower extract.

Authors+Show Affiliations

Department of Biochemistry, Faculty of Science, Annamalai University, Annamalai Nagar, Tamil Nadu, India.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12619885

Citation

Latha, Muniappan, and Leelavinothan Pari. "Preventive Effects of Cassia Auriculata L. Flowers On Brain Lipid Peroxidation in Rats Treated With Streptozotocin." Molecular and Cellular Biochemistry, vol. 243, no. 1-2, 2003, pp. 23-8.
Latha M, Pari L. Preventive effects of Cassia auriculata L. flowers on brain lipid peroxidation in rats treated with streptozotocin. Mol Cell Biochem. 2003;243(1-2):23-8.
Latha, M., & Pari, L. (2003). Preventive effects of Cassia auriculata L. flowers on brain lipid peroxidation in rats treated with streptozotocin. Molecular and Cellular Biochemistry, 243(1-2), 23-8.
Latha M, Pari L. Preventive Effects of Cassia Auriculata L. Flowers On Brain Lipid Peroxidation in Rats Treated With Streptozotocin. Mol Cell Biochem. 2003;243(1-2):23-8. PubMed PMID: 12619885.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Preventive effects of Cassia auriculata L. flowers on brain lipid peroxidation in rats treated with streptozotocin. AU - Latha,Muniappan, AU - Pari,Leelavinothan, PY - 2003/3/7/pubmed PY - 2003/12/3/medline PY - 2003/3/7/entrez SP - 23 EP - 8 JF - Molecular and cellular biochemistry JO - Mol Cell Biochem VL - 243 IS - 1-2 N2 - The effect of aqueous extract of the flowers of Cassia auriculata were examined on antioxidants and lipid peroxidation in the brain of streptozotocin diabetic rats. Significant increase in the activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase and reduced glutathione were observed in brain on treatment with Cassia auriculata flower extract (CFEt) and glibenclamide. Both the treated groups showed significant decrease in thiobarbituric reactive substances (TBARS) and hydroperoxide formation in brain, suggesting its role in protection against lipid peroxidation induced membrane damage. Since the study of induction of the antioxidant enzymes is considered to be a reliable marker for evaluating the antiperoxidative efficacy of medicinal plant, these findings are suggestions of possible antiperoxidative role played by Cassia auriculata flower extract. SN - 0300-8177 UR - https://www.unboundmedicine.com/medline/citation/12619885/Preventive_effects_of_Cassia_auriculata_L__flowers_on_brain_lipid_peroxidation_in_rats_treated_with_streptozotocin_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=12619885.ui DB - PRIME DP - Unbound Medicine ER -