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[Ischemic heart disease and gastro-oesophageal reflux disease--simultaneous 24 monitoring of ECG and oesophageal pH].
Przegl Lek 2002; 59(9):675-7PL

Abstract

AIM

To determine the correlation between episodes of ischaemia in ECG recordings with pathologic gastro-esophageal reflux during simultaneous 24 hour monitoring of ECG and oesophageal pH.

METHODS

Simultaneous 24 hour monitoring of ECG and oesophageal pH was performed in 30 patients (p) (26 M/4F, aged 39-74) with coronary artery disease of CCS class II-III, CAD was confirmed in coronary angiography. Analysis of the oesophageal pH was performed by using the Polygram programme (PW-version 2.04 Esophogram-version 2.01). ST depression > 1 mm and lasting at least 1 min was regarded as significant in ECG monitoring. Pathologic gastro-esophageal reflux was defined as a drop in pH < 4 lasting more than 5 min. Gastrooesophageal reflux disease (GERD) was diagnosed when a drop in pH < 4 lasted for more than 5% of the monitoring period. Gastro-oesophageal reflux dependent ST depression was defined as an ST depression that occurred during reflux episode and lasted up until 10 min from the end of the reflux.

RESULTS

26 patients (87%) had a total of 116 episodes of ST depression and 21 out of the 116 episodes (18%) were Gastro-oesophageal reflux time dependent. Fifteen patients (50%), had at least one episode of ST depression, depending on the time of reflux. Pathologic gastro-esophageal reflux was present in 25 patients (85%). In 14 patients (46.6%), the GERD pH criteria were fulfilled. In this group of patients, there was a significantly longer time of total ST depression (total ischaemic burden).

CONCLUSIONS

1. GERD is a frequent disease in patients with angiographically proven coronary artery disease. 2. Pathological gastroesophageal reflux can induce myocardial ischaemia, which can be determined by analysis of ST depression during 24 hour monitoring of ECG.

Authors+Show Affiliations

Zakład Kardiologii Inwazyjnej AM 15-276 Białystok ul. M. Skłodowskiej-Curie 24A. proprzem@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

pol

PubMed ID

12632883

Citation

Dobrzycki, Sławomir, et al. "[Ischemic Heart Disease and Gastro-oesophageal Reflux Disease--simultaneous 24 Monitoring of ECG and Oesophageal PH]." Przeglad Lekarski, vol. 59, no. 9, 2002, pp. 675-7.
Dobrzycki S, Baniukiewicz A, Musiał WJ, et al. [Ischemic heart disease and gastro-oesophageal reflux disease--simultaneous 24 monitoring of ECG and oesophageal pH]. Prz Lek. 2002;59(9):675-7.
Dobrzycki, S., Baniukiewicz, A., Musiał, W. J., Skrodzka, D., Zaremba-Woroniecka, A., Korecki, J., ... Kochman, W. (2002). [Ischemic heart disease and gastro-oesophageal reflux disease--simultaneous 24 monitoring of ECG and oesophageal pH]. Przeglad Lekarski, 59(9), pp. 675-7.
Dobrzycki S, et al. [Ischemic Heart Disease and Gastro-oesophageal Reflux Disease--simultaneous 24 Monitoring of ECG and Oesophageal PH]. Prz Lek. 2002;59(9):675-7. PubMed PMID: 12632883.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Ischemic heart disease and gastro-oesophageal reflux disease--simultaneous 24 monitoring of ECG and oesophageal pH]. AU - Dobrzycki,Sławomir, AU - Baniukiewicz,Andrzej, AU - Musiał,Włodzimierz J, AU - Skrodzka,Dorota, AU - Zaremba-Woroniecka,Anna, AU - Korecki,Janusz, AU - Łaszewicz,Wiktor, AU - Kralisz,Paweł, AU - Paruk,Jan, AU - Kochman,Wacław, PY - 2003/3/14/pubmed PY - 2003/5/16/medline PY - 2003/3/14/entrez SP - 675 EP - 7 JF - Przeglad lekarski JO - Prz. Lek. VL - 59 IS - 9 N2 - AIM: To determine the correlation between episodes of ischaemia in ECG recordings with pathologic gastro-esophageal reflux during simultaneous 24 hour monitoring of ECG and oesophageal pH. METHODS: Simultaneous 24 hour monitoring of ECG and oesophageal pH was performed in 30 patients (p) (26 M/4F, aged 39-74) with coronary artery disease of CCS class II-III, CAD was confirmed in coronary angiography. Analysis of the oesophageal pH was performed by using the Polygram programme (PW-version 2.04 Esophogram-version 2.01). ST depression > 1 mm and lasting at least 1 min was regarded as significant in ECG monitoring. Pathologic gastro-esophageal reflux was defined as a drop in pH < 4 lasting more than 5 min. Gastrooesophageal reflux disease (GERD) was diagnosed when a drop in pH < 4 lasted for more than 5% of the monitoring period. Gastro-oesophageal reflux dependent ST depression was defined as an ST depression that occurred during reflux episode and lasted up until 10 min from the end of the reflux. RESULTS: 26 patients (87%) had a total of 116 episodes of ST depression and 21 out of the 116 episodes (18%) were Gastro-oesophageal reflux time dependent. Fifteen patients (50%), had at least one episode of ST depression, depending on the time of reflux. Pathologic gastro-esophageal reflux was present in 25 patients (85%). In 14 patients (46.6%), the GERD pH criteria were fulfilled. In this group of patients, there was a significantly longer time of total ST depression (total ischaemic burden). CONCLUSIONS: 1. GERD is a frequent disease in patients with angiographically proven coronary artery disease. 2. Pathological gastroesophageal reflux can induce myocardial ischaemia, which can be determined by analysis of ST depression during 24 hour monitoring of ECG. SN - 0033-2240 UR - https://www.unboundmedicine.com/medline/citation/12632883/[Ischemic_heart_disease_and_gastro_oesophageal_reflux_disease__simultaneous_24_monitoring_of_ECG_and_oesophageal_pH]_ L2 - http://www.diseaseinfosearch.org/result/130 DB - PRIME DP - Unbound Medicine ER -