Tags

Type your tag names separated by a space and hit enter

Regional differences in Finland in the prevalence of rheumatoid factor in the presence and absence of arthritis.
Ann Rheum Dis. 2003 Apr; 62(4):353-5.AR

Abstract

OBJECTIVES

To look for possible regional differences in the prevalence of rheumatoid factor (RF) in the presence and absence of arthritis.

METHODS

The study covered a representative sample of the Finnish population aged 30 years or over, primarily comprising 8000 people, of whom 7217 participated in the field survey carried out in 1978-80. RF from serum samples from 7116 subjects was determined by the Waaler-Rose (sensitised sheep cell agglutination) test. Titres >or=32 were regarded as positive and titres >or=128 as strongly positive. Arthritis was diagnosed by a thorough clinical examination.

RESULTS

In the absence of arthritis the prevalence of positive and strongly positive RF reactions was 2.1% and 1.0%, respectively. The lowest prevalence of strongly "false positive" RF occurred in south western Finland. After adjustment for age, sex, smoking, and coffee consumption the odds ratio of having a strongly "false positive" RF reaction in eastern Finland was 3.16 (95% confidence interval 1.29 to 7.72) and in northern Finland 2.94 (1.13 to 7.64) compared with south western Finland. The corresponding odds ratio of strongly RF positive arthritis in eastern Finland was 5.08 (1.41 to 18.27).

CONCLUSION

Regional differences are found in the prevalence of a strongly positive RF reaction in the Finnish population. The findings are in accordance with recent results from another study concerning regional differences in the incidence of rheumatoid arthritis in Finland.

Authors+Show Affiliations

Department of Medicine, Kuopio University Hospital, Kuopio, Finland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12634237

Citation

Korpilähde, T, et al. "Regional Differences in Finland in the Prevalence of Rheumatoid Factor in the Presence and Absence of Arthritis." Annals of the Rheumatic Diseases, vol. 62, no. 4, 2003, pp. 353-5.
Korpilähde T, Heliövaara M, Kaipiainen-Seppänen O, et al. Regional differences in Finland in the prevalence of rheumatoid factor in the presence and absence of arthritis. Ann Rheum Dis. 2003;62(4):353-5.
Korpilähde, T., Heliövaara, M., Kaipiainen-Seppänen, O., Knekt, P., & Aho, K. (2003). Regional differences in Finland in the prevalence of rheumatoid factor in the presence and absence of arthritis. Annals of the Rheumatic Diseases, 62(4), 353-5.
Korpilähde T, et al. Regional Differences in Finland in the Prevalence of Rheumatoid Factor in the Presence and Absence of Arthritis. Ann Rheum Dis. 2003;62(4):353-5. PubMed PMID: 12634237.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Regional differences in Finland in the prevalence of rheumatoid factor in the presence and absence of arthritis. AU - Korpilähde,T, AU - Heliövaara,M, AU - Kaipiainen-Seppänen,O, AU - Knekt,P, AU - Aho,K, PY - 2003/3/14/pubmed PY - 2003/5/14/medline PY - 2003/3/14/entrez SP - 353 EP - 5 JF - Annals of the rheumatic diseases JO - Ann Rheum Dis VL - 62 IS - 4 N2 - OBJECTIVES: To look for possible regional differences in the prevalence of rheumatoid factor (RF) in the presence and absence of arthritis. METHODS: The study covered a representative sample of the Finnish population aged 30 years or over, primarily comprising 8000 people, of whom 7217 participated in the field survey carried out in 1978-80. RF from serum samples from 7116 subjects was determined by the Waaler-Rose (sensitised sheep cell agglutination) test. Titres >or=32 were regarded as positive and titres >or=128 as strongly positive. Arthritis was diagnosed by a thorough clinical examination. RESULTS: In the absence of arthritis the prevalence of positive and strongly positive RF reactions was 2.1% and 1.0%, respectively. The lowest prevalence of strongly "false positive" RF occurred in south western Finland. After adjustment for age, sex, smoking, and coffee consumption the odds ratio of having a strongly "false positive" RF reaction in eastern Finland was 3.16 (95% confidence interval 1.29 to 7.72) and in northern Finland 2.94 (1.13 to 7.64) compared with south western Finland. The corresponding odds ratio of strongly RF positive arthritis in eastern Finland was 5.08 (1.41 to 18.27). CONCLUSION: Regional differences are found in the prevalence of a strongly positive RF reaction in the Finnish population. The findings are in accordance with recent results from another study concerning regional differences in the incidence of rheumatoid arthritis in Finland. SN - 0003-4967 UR - https://www.unboundmedicine.com/medline/citation/12634237/Regional_differences_in_Finland_in_the_prevalence_of_rheumatoid_factor_in_the_presence_and_absence_of_arthritis_ L2 - https://ard.bmj.com/lookup/pmidlookup?view=long&pmid=12634237 DB - PRIME DP - Unbound Medicine ER -