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Prospective evaluation of the value of combined mammographic and sonographic assessment in patients with palpable abnormalities of the breast.
J Ultrasound Med. 2003 Mar; 22(3):263-8; quiz 269-70.JU

Abstract

OBJECTIVE

To evaluate the role of combined mammographic and sonographic imaging in patients with palpable abnormalities of the breast.

METHODS

Four hundred eleven consecutive cases of palpable abnormalities of the breast underwent combined mammographic and sonographic evaluation. Patients who did not undergo biopsy had imaging and clinical follow-up; the mean follow-up period was 28.9 months (range, 24-33 months).

RESULTS

One hundred sixty-five (40.1%) of 411 palpable abnormalities had a benign assessment; 97 (58.7%) of the 165 benign lesions were visible on both mammography and sonography; 66 (40%) of 165 benign lesions were mammographically occult and identified at sonographic evaluation. In 60 (14.6%) of the 411 cases, imaging evaluation resulted in a suspicious assessment; 49 (81.7%) of the 60 lesions categorized as suspicious underwent biopsy; 14 (28.5%) of 49 lesions were histologically proved to be carcinoma. Nineteen (31.6%) of the 60 lesions categorized as suspicious were mammographically occult and identified only on sonography; 14 (73.7%) of these 19 lesions underwent biopsy; 12 (63.1%) of 19 were benign, and 2 (10.5%) were malignant. One hundred eighty-six (45.2%) of the 411 palpable abnormalities had negative imaging assessment findings; 12 patients with negative imaging findings underwent biopsy, and all had benign findings. The sensitivity (14 of 14) and negative predictive value (186 of 186) for a combined mammographic and sonographic assessment were 100%; the specificity was 80.1% (186 of 232).

CONCLUSIONS

Cancer was diagnosed in 14 (3.4%) of 411 women who underwent combined imaging for palpable abnormalities of the breast. Combined mammographic and sonographic assessment was shown to be very helpful in identifying benign as well as malignant lesions causing palpable abnormalities of the breast.

Authors+Show Affiliations

Department of Radiology, Baylor College of Medicine and The Woman's Hospital of Texas, Houston, Texas 77054, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

12636326

Citation

Shetty, Mahesh K., et al. "Prospective Evaluation of the Value of Combined Mammographic and Sonographic Assessment in Patients With Palpable Abnormalities of the Breast." Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine, vol. 22, no. 3, 2003, pp. 263-8; quiz 269-70.
Shetty MK, Shah YP, Sharman RS. Prospective evaluation of the value of combined mammographic and sonographic assessment in patients with palpable abnormalities of the breast. J Ultrasound Med. 2003;22(3):263-8; quiz 269-70.
Shetty, M. K., Shah, Y. P., & Sharman, R. S. (2003). Prospective evaluation of the value of combined mammographic and sonographic assessment in patients with palpable abnormalities of the breast. Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine, 22(3), 263-8; quiz 269-70.
Shetty MK, Shah YP, Sharman RS. Prospective Evaluation of the Value of Combined Mammographic and Sonographic Assessment in Patients With Palpable Abnormalities of the Breast. J Ultrasound Med. 2003;22(3):263-8; quiz 269-70. PubMed PMID: 12636326.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prospective evaluation of the value of combined mammographic and sonographic assessment in patients with palpable abnormalities of the breast. AU - Shetty,Mahesh K, AU - Shah,Yogesh P, AU - Sharman,Ralph S, PY - 2003/3/15/pubmed PY - 2003/7/12/medline PY - 2003/3/15/entrez SP - 263-8; quiz 269-70 JF - Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine JO - J Ultrasound Med VL - 22 IS - 3 N2 - OBJECTIVE: To evaluate the role of combined mammographic and sonographic imaging in patients with palpable abnormalities of the breast. METHODS: Four hundred eleven consecutive cases of palpable abnormalities of the breast underwent combined mammographic and sonographic evaluation. Patients who did not undergo biopsy had imaging and clinical follow-up; the mean follow-up period was 28.9 months (range, 24-33 months). RESULTS: One hundred sixty-five (40.1%) of 411 palpable abnormalities had a benign assessment; 97 (58.7%) of the 165 benign lesions were visible on both mammography and sonography; 66 (40%) of 165 benign lesions were mammographically occult and identified at sonographic evaluation. In 60 (14.6%) of the 411 cases, imaging evaluation resulted in a suspicious assessment; 49 (81.7%) of the 60 lesions categorized as suspicious underwent biopsy; 14 (28.5%) of 49 lesions were histologically proved to be carcinoma. Nineteen (31.6%) of the 60 lesions categorized as suspicious were mammographically occult and identified only on sonography; 14 (73.7%) of these 19 lesions underwent biopsy; 12 (63.1%) of 19 were benign, and 2 (10.5%) were malignant. One hundred eighty-six (45.2%) of the 411 palpable abnormalities had negative imaging assessment findings; 12 patients with negative imaging findings underwent biopsy, and all had benign findings. The sensitivity (14 of 14) and negative predictive value (186 of 186) for a combined mammographic and sonographic assessment were 100%; the specificity was 80.1% (186 of 232). CONCLUSIONS: Cancer was diagnosed in 14 (3.4%) of 411 women who underwent combined imaging for palpable abnormalities of the breast. Combined mammographic and sonographic assessment was shown to be very helpful in identifying benign as well as malignant lesions causing palpable abnormalities of the breast. SN - 0278-4297 UR - https://www.unboundmedicine.com/medline/citation/12636326/Prospective_evaluation_of_the_value_of_combined_mammographic_and_sonographic_assessment_in_patients_with_palpable_abnormalities_of_the_breast_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0278-4297&date=2003&volume=22&issue=3&spage=263 DB - PRIME DP - Unbound Medicine ER -