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Acute renal failure in the ICU: assessing the utility of continuous renal replacement.
J Crit Care. 2003 Mar; 18(1):48-51.JC

Abstract

Acute renal failure (ARF) in the ICU patient still remains a common problem and is associated with increased morbidity, mortality, and cost. Potential advantages of continuous renal replacement (CRRT), compared with intermittent hemodialysis (IHD) include enhanced hemodynamic stability, increased solute removal, and greater ultrafiltration. Although it was hoped that CRRT would lead to improvement in patient outcomes, there are few prospective, randomized clinical studies comparing this modality with conventional hemodialysis in the treatment of patients with ARF. The difficulties associated with designing such prospective studies are the complex status of the medical patients and the ethical dilemma of randomizing patients to a certain dialysis modality. At this time, there is no evidence to support the assertion that CRRT improves clinical outcomes compared with IHD.

Authors+Show Affiliations

Division of Nephrology, Department of Medicine, London Health Sciences Centre, London, Ontario.No affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Review

Language

eng

PubMed ID

12640614

Citation

Hanson, Garth, and Louise Moist. "Acute Renal Failure in the ICU: Assessing the Utility of Continuous Renal Replacement." Journal of Critical Care, vol. 18, no. 1, 2003, pp. 48-51.
Hanson G, Moist L. Acute renal failure in the ICU: assessing the utility of continuous renal replacement. J Crit Care. 2003;18(1):48-51.
Hanson, G., & Moist, L. (2003). Acute renal failure in the ICU: assessing the utility of continuous renal replacement. Journal of Critical Care, 18(1), 48-51.
Hanson G, Moist L. Acute Renal Failure in the ICU: Assessing the Utility of Continuous Renal Replacement. J Crit Care. 2003;18(1):48-51. PubMed PMID: 12640614.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute renal failure in the ICU: assessing the utility of continuous renal replacement. AU - Hanson,Garth, AU - Moist,Louise, PY - 2003/3/18/pubmed PY - 2003/7/2/medline PY - 2003/3/18/entrez SP - 48 EP - 51 JF - Journal of critical care JO - J Crit Care VL - 18 IS - 1 N2 - Acute renal failure (ARF) in the ICU patient still remains a common problem and is associated with increased morbidity, mortality, and cost. Potential advantages of continuous renal replacement (CRRT), compared with intermittent hemodialysis (IHD) include enhanced hemodynamic stability, increased solute removal, and greater ultrafiltration. Although it was hoped that CRRT would lead to improvement in patient outcomes, there are few prospective, randomized clinical studies comparing this modality with conventional hemodialysis in the treatment of patients with ARF. The difficulties associated with designing such prospective studies are the complex status of the medical patients and the ethical dilemma of randomizing patients to a certain dialysis modality. At this time, there is no evidence to support the assertion that CRRT improves clinical outcomes compared with IHD. SN - 0883-9441 UR - https://www.unboundmedicine.com/medline/citation/12640614/Acute_renal_failure_in_the_ICU:_assessing_the_utility_of_continuous_renal_replacement_ DB - PRIME DP - Unbound Medicine ER -