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[Cerebral sinus thrombosis in Behçet disease: case report and review of the literature].
Klin Monbl Augenheilkd. 2003 Mar; 220(3):186-8.KM

Abstract

BACKGROUND

Behçet's disease is a chronic inflammatory disorder, clinically characterised by multisystemic vasculitis. Primary neurologic involvement in childhood is quite exceptional. We report a case of a child with recurrent venous thrombosis of the dural sinus. Behçet's disease was diagnosed.

HISTORY AND SIGNS

A 13-year-old boy from Eritrea was referred to our clinic with severe headaches and photophobia one month after onset. Ophthalmological examination disclosed a bilateral papilledema. Recurrent oral ulcers and pseudo-folliculitis were present. Pathergy test was positive.

THERAPY AND OUTCOME

Complementary investigations disclosed an inflammatory syndrome. Computertomography was normal. Cranial magnetic resonance venography disclosed multiple cerebral sinus thrombosis (superior sagittal sinus, sigmoid sinus and lateral left sinus). There was no evidence of infectious, inflammatory or hypercoagulation disorder. A Behçet's disease was diagnosed based on the medical history and clinical examination. Whilst his general health deteriorated rapidly before treatment, he improved quickly after the onset of therapy with immunosuppression (Prednisone and Ciclosporine) in combination with anticoagulation (coumarin/Sintrom).

CONCLUSION

Behçet's disease is uncommon and difficult to diagnose in children. Neurologic involvement as a first presentation is rarely described, but might be underestimated. We emphasise, therefore, the systematic application of magnetic resonance venography in children with unclear persistent headaches.

Authors+Show Affiliations

Clinique d'Ophtalmologie, Département de neurosciences cliniques, Hôpitaux Universitaires de Genève, Genève, Suisse. Karla.Chaloupka@hcuge.chNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

fre

PubMed ID

12664376

Citation

Chaloupka, Karla, et al. "[Cerebral Sinus Thrombosis in Behçet Disease: Case Report and Review of the Literature]." Klinische Monatsblatter Fur Augenheilkunde, vol. 220, no. 3, 2003, pp. 186-8.
Chaloupka K, Baglivo E, Hofer M, et al. [Cerebral sinus thrombosis in Behçet disease: case report and review of the literature]. Klin Monbl Augenheilkd. 2003;220(3):186-8.
Chaloupka, K., Baglivo, E., Hofer, M., Chizzolini, C., Delavelle, J., Rossillion, B., & Safran, A. B. (2003). [Cerebral sinus thrombosis in Behçet disease: case report and review of the literature]. Klinische Monatsblatter Fur Augenheilkunde, 220(3), 186-8.
Chaloupka K, et al. [Cerebral Sinus Thrombosis in Behçet Disease: Case Report and Review of the Literature]. Klin Monbl Augenheilkd. 2003;220(3):186-8. PubMed PMID: 12664376.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Cerebral sinus thrombosis in Behçet disease: case report and review of the literature]. AU - Chaloupka,Karla, AU - Baglivo,Edoardo, AU - Hofer,Michael, AU - Chizzolini,Carlo, AU - Delavelle,Jacqueline, AU - Rossillion,Béatrice, AU - Safran,Avinoam B, PY - 2003/3/29/pubmed PY - 2003/10/30/medline PY - 2003/3/29/entrez SP - 186 EP - 8 JF - Klinische Monatsblatter fur Augenheilkunde JO - Klin Monbl Augenheilkd VL - 220 IS - 3 N2 - BACKGROUND: Behçet's disease is a chronic inflammatory disorder, clinically characterised by multisystemic vasculitis. Primary neurologic involvement in childhood is quite exceptional. We report a case of a child with recurrent venous thrombosis of the dural sinus. Behçet's disease was diagnosed. HISTORY AND SIGNS: A 13-year-old boy from Eritrea was referred to our clinic with severe headaches and photophobia one month after onset. Ophthalmological examination disclosed a bilateral papilledema. Recurrent oral ulcers and pseudo-folliculitis were present. Pathergy test was positive. THERAPY AND OUTCOME: Complementary investigations disclosed an inflammatory syndrome. Computertomography was normal. Cranial magnetic resonance venography disclosed multiple cerebral sinus thrombosis (superior sagittal sinus, sigmoid sinus and lateral left sinus). There was no evidence of infectious, inflammatory or hypercoagulation disorder. A Behçet's disease was diagnosed based on the medical history and clinical examination. Whilst his general health deteriorated rapidly before treatment, he improved quickly after the onset of therapy with immunosuppression (Prednisone and Ciclosporine) in combination with anticoagulation (coumarin/Sintrom). CONCLUSION: Behçet's disease is uncommon and difficult to diagnose in children. Neurologic involvement as a first presentation is rarely described, but might be underestimated. We emphasise, therefore, the systematic application of magnetic resonance venography in children with unclear persistent headaches. SN - 0023-2165 UR - https://www.unboundmedicine.com/medline/citation/12664376/[Cerebral_sinus_thrombosis_in_Behçet_disease:_case_report_and_review_of_the_literature]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2003-38186 DB - PRIME DP - Unbound Medicine ER -