TY - JOUR T1 - Voluntary activation and decreased force production of the quadriceps femoris muscle after total knee arthroplasty. AU - Mizner,Ryan L, AU - Stevens,Jennifer E, AU - Snyder-Mackler,Lynn, PY - 2003/4/1/pubmed PY - 2003/4/16/medline PY - 2003/4/1/entrez SP - 359 EP - 65 JF - Physical therapy JO - Phys Ther VL - 83 IS - 4 N2 - BACKGROUND AND PURPOSE: Quadriceps femoris muscle weakness as manifested by a decrease in force-generating capability is a persistent problem after total knee arthroplasty (TKA). The authors hypothesized that (1) patients with a TKA would have decreased quadriceps femoris muscle performance (weakness) and impaired volitional activation when compared with a group of older adults without knee pathology, (2) pain and age would account for a large portion of the variability in volitional activation after surgery, and (3) volitional activation in the TKA group would account for a large portion of the variability in force production. SUBJECTS: Comparison subjects were 52 volunteers (mean age=72.2 years, SD=5.34, range=64-85). The TKA group comprised 52 patients (mean age=64.9 years, SD=7.72, range=49-78) with a diagnosis of osteoarthritis who had undergone a tricompartmental, cemented TKA. METHODS: Knee extension force was measured using a burst superimposition technique, where a supramaximal burst of electrical stimulation was superimposed on a maximal voluntary isometric contraction (MVIC). The amount of failure of volitional activation is determined by the amount of electrical augmentation of force beyond a person's MVIC at the instant of the application of the electrical burst. RESULTS: The average normalized knee extension force of the TKA group was 64% lower than that of the comparison group. The average volitional activation deficit in the TKA group (26%) was 4 times as great as the comparison group's deficit (6%). Age did not correlate with quadriceps femoris muscle activation, and knee pain explained only a small portion of the variance in knee extension force (r2=.17). Volitional activation was highly correlated with knee extension force production (r2=.65). DISCUSSION AND CONCLUSION: Considerable quadriceps femoris muscle inhibition after surgery has several implications for recovery. Rehabilitation programs that focus on volitional exercise alone are unlikely to overcome this pronounced failure of activation. Early interventions focused at improving quadriceps femoris muscle voluntary activation may improve efforts to restore muscle force. SN - 0031-9023 UR - https://www.unboundmedicine.com/medline/citation/12665406/Voluntary_activation_and_decreased_force_production_of_the_quadriceps_femoris_muscle_after_total_knee_arthroplasty_ L2 - https://ClinicalTrials.gov/search/term=12665406 [PUBMED-IDS] DB - PRIME DP - Unbound Medicine ER -