Tags

Type your tag names separated by a space and hit enter

Elevated intracranial pressure detected by bedside emergency ultrasonography of the optic nerve sheath.
Acad Emerg Med. 2003 Apr; 10(4):376-81.AE

Abstract

Patients with altered level of consciousness may be suffering from elevated intracranial pressure (EICP) from a variety of causes. A rapid, portable, and noninvasive means of detecting EICP is desirable when conventional imaging methods are unavailable.

OBJECTIVES

The hypothesis of this study was that ultrasound (US) measurement of the optic nerve sheath diameter (ONSD) could accurately predict the presence of EICP.

METHODS

The authors performed a prospective, blinded observational study on emergency department (ED) patients with a suspicion of EICP due to possible focal intracranial pathology. The study was conducted at a large community ED with an emergency medicine residency program and took place over a six-month period. Patients suspected of having EICP by an ED attending were enrolled when study physicians were available. Unstable patients were excluded. ONSD was measured 3 mm behind the globe using a 10-MHz linear probe on the closed eyelids of supine patients, bilaterally. Based on prior literature, an ONSD above 5 mm on ultrasound was considered abnormal. Computed tomography (CT) findings defined as indicative of EICP were the presence of mass effect with a midline shift 3 mm or more, a collapsed third ventricle, hydrocephalus, the effacement of sulci with evidence of significant edema, and abnormal mesencephalic cisterns. For each patient, the average of the two ONSD measurements was calculated and his or her head CT scans were evaluated for signs of EICP. Student's t-test was used to compare ONSDs in the normal and EICP groups. Sensitivity, specificity, and positive and negative predictive values were calculated.

RESULTS

Thirty-five patients were enrolled; 14 had CT results consistent with EICP. All cases of CT-determined EICP were correctly predicted by ONSD over 5 mm on US. One patient with ONSD of 5.7 mm in one eye and 3.7 mm in the other on US had a mass abutting the ipsilateral optic nerve; no shift was seen on CT. He was placed in the EICP category on his data collection sheet. The mean ONSD for the 14 patients with CT evidence of EICP was 6.27 mm (95% CI = 5.6 to 6.89); the mean ONSD for the others was 4.42 mm (95% CI = 4.15 to 4.72). The difference of 1.85 mm (95% CI = 1.23 to 2.39 mm) yielded a p = 0.001. The sensitivity and specificity for ONSD, when compared with CT results, were 100% and 95%, respectively. The positive and negative predictive values were 93% and 100%, respectively.

CONCLUSIONS

Despite small numbers and selection bias, this study suggests that bedside ED US may be useful in the diagnosis of EICP.

Authors+Show Affiliations

Department of Emergency Medicine, Medical College of Georgia, 1120 15th Street, AF-2056, Augusta, GA 30912-4007, USA. blaivas@pyro.netNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12670853

Citation

Blaivas, Michael, et al. "Elevated Intracranial Pressure Detected By Bedside Emergency Ultrasonography of the Optic Nerve Sheath." Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine, vol. 10, no. 4, 2003, pp. 376-81.
Blaivas M, Theodoro D, Sierzenski PR. Elevated intracranial pressure detected by bedside emergency ultrasonography of the optic nerve sheath. Acad Emerg Med. 2003;10(4):376-81.
Blaivas, M., Theodoro, D., & Sierzenski, P. R. (2003). Elevated intracranial pressure detected by bedside emergency ultrasonography of the optic nerve sheath. Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine, 10(4), 376-81.
Blaivas M, Theodoro D, Sierzenski PR. Elevated Intracranial Pressure Detected By Bedside Emergency Ultrasonography of the Optic Nerve Sheath. Acad Emerg Med. 2003;10(4):376-81. PubMed PMID: 12670853.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Elevated intracranial pressure detected by bedside emergency ultrasonography of the optic nerve sheath. AU - Blaivas,Michael, AU - Theodoro,Daniel, AU - Sierzenski,Paul R, PY - 2003/4/3/pubmed PY - 2003/9/13/medline PY - 2003/4/3/entrez SP - 376 EP - 81 JF - Academic emergency medicine : official journal of the Society for Academic Emergency Medicine JO - Acad Emerg Med VL - 10 IS - 4 N2 - UNLABELLED: Patients with altered level of consciousness may be suffering from elevated intracranial pressure (EICP) from a variety of causes. A rapid, portable, and noninvasive means of detecting EICP is desirable when conventional imaging methods are unavailable. OBJECTIVES: The hypothesis of this study was that ultrasound (US) measurement of the optic nerve sheath diameter (ONSD) could accurately predict the presence of EICP. METHODS: The authors performed a prospective, blinded observational study on emergency department (ED) patients with a suspicion of EICP due to possible focal intracranial pathology. The study was conducted at a large community ED with an emergency medicine residency program and took place over a six-month period. Patients suspected of having EICP by an ED attending were enrolled when study physicians were available. Unstable patients were excluded. ONSD was measured 3 mm behind the globe using a 10-MHz linear probe on the closed eyelids of supine patients, bilaterally. Based on prior literature, an ONSD above 5 mm on ultrasound was considered abnormal. Computed tomography (CT) findings defined as indicative of EICP were the presence of mass effect with a midline shift 3 mm or more, a collapsed third ventricle, hydrocephalus, the effacement of sulci with evidence of significant edema, and abnormal mesencephalic cisterns. For each patient, the average of the two ONSD measurements was calculated and his or her head CT scans were evaluated for signs of EICP. Student's t-test was used to compare ONSDs in the normal and EICP groups. Sensitivity, specificity, and positive and negative predictive values were calculated. RESULTS: Thirty-five patients were enrolled; 14 had CT results consistent with EICP. All cases of CT-determined EICP were correctly predicted by ONSD over 5 mm on US. One patient with ONSD of 5.7 mm in one eye and 3.7 mm in the other on US had a mass abutting the ipsilateral optic nerve; no shift was seen on CT. He was placed in the EICP category on his data collection sheet. The mean ONSD for the 14 patients with CT evidence of EICP was 6.27 mm (95% CI = 5.6 to 6.89); the mean ONSD for the others was 4.42 mm (95% CI = 4.15 to 4.72). The difference of 1.85 mm (95% CI = 1.23 to 2.39 mm) yielded a p = 0.001. The sensitivity and specificity for ONSD, when compared with CT results, were 100% and 95%, respectively. The positive and negative predictive values were 93% and 100%, respectively. CONCLUSIONS: Despite small numbers and selection bias, this study suggests that bedside ED US may be useful in the diagnosis of EICP. SN - 1069-6563 UR - https://www.unboundmedicine.com/medline/citation/12670853/Elevated_intracranial_pressure_detected_by_bedside_emergency_ultrasonography_of_the_optic_nerve_sheath_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1069-6563&date=2003&volume=10&issue=4&spage=376 DB - PRIME DP - Unbound Medicine ER -