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Nutrition and breast cancer risk by age 50: a population-based case-control study in Germany.
Nutr Cancer. 2002; 44(1):23-34.NC

Abstract

Diet is recognized to play a role in the occurrence of breast cancer; however, the data are inconsistent. The goal of this study was to determine the influence of dietary factors on breast cancer risk among women up to 50 yr of age in a German population. A population-based case-control study was conducted including 706 cases and 1,381 controls. In addition to a risk factor questionnaire, a subgroup of 355 cases and 838 controls completed a food frequency questionnaire. Breast cancer risk was inversely associated with vegetable consumption (P for trend = 0.034). The odds ratio for the fourth quartile of vegetable intake compared with the first quartile was 0.64 (95% confidence interval = 0.43-0.96). Breast cancer risk increased with a higher consumption of red meat (P for trend = 0.016); women with the highest consumption level had an 85% elevated breast cancer risk compared with the lowest quartile (95% confidence interval = 1.23-2.78). When only premenopausal women were considered, the protective effect of vegetable intake and the positive association with meat intake were even stronger. These results are compatible with the international recommendations for a breast cancer preventive diet and suggest that the favorable effect of a diet high in vegetables and low in red meat, especially beef, may be stronger in premenopausal women.

Authors+Show Affiliations

Department of Clinical Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12672638

Citation

Hermann, Silke, et al. "Nutrition and Breast Cancer Risk By Age 50: a Population-based Case-control Study in Germany." Nutrition and Cancer, vol. 44, no. 1, 2002, pp. 23-34.
Hermann S, Linseisen J, Chang-Claude J. Nutrition and breast cancer risk by age 50: a population-based case-control study in Germany. Nutr Cancer. 2002;44(1):23-34.
Hermann, S., Linseisen, J., & Chang-Claude, J. (2002). Nutrition and breast cancer risk by age 50: a population-based case-control study in Germany. Nutrition and Cancer, 44(1), 23-34.
Hermann S, Linseisen J, Chang-Claude J. Nutrition and Breast Cancer Risk By Age 50: a Population-based Case-control Study in Germany. Nutr Cancer. 2002;44(1):23-34. PubMed PMID: 12672638.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nutrition and breast cancer risk by age 50: a population-based case-control study in Germany. AU - Hermann,Silke, AU - Linseisen,Jakob, AU - Chang-Claude,Jenny, PY - 2003/4/4/pubmed PY - 2003/5/30/medline PY - 2003/4/4/entrez SP - 23 EP - 34 JF - Nutrition and cancer JO - Nutr Cancer VL - 44 IS - 1 N2 - Diet is recognized to play a role in the occurrence of breast cancer; however, the data are inconsistent. The goal of this study was to determine the influence of dietary factors on breast cancer risk among women up to 50 yr of age in a German population. A population-based case-control study was conducted including 706 cases and 1,381 controls. In addition to a risk factor questionnaire, a subgroup of 355 cases and 838 controls completed a food frequency questionnaire. Breast cancer risk was inversely associated with vegetable consumption (P for trend = 0.034). The odds ratio for the fourth quartile of vegetable intake compared with the first quartile was 0.64 (95% confidence interval = 0.43-0.96). Breast cancer risk increased with a higher consumption of red meat (P for trend = 0.016); women with the highest consumption level had an 85% elevated breast cancer risk compared with the lowest quartile (95% confidence interval = 1.23-2.78). When only premenopausal women were considered, the protective effect of vegetable intake and the positive association with meat intake were even stronger. These results are compatible with the international recommendations for a breast cancer preventive diet and suggest that the favorable effect of a diet high in vegetables and low in red meat, especially beef, may be stronger in premenopausal women. SN - 0163-5581 UR - https://www.unboundmedicine.com/medline/citation/12672638/Nutrition_and_breast_cancer_risk_by_age_50:_a_population_based_case_control_study_in_Germany_ L2 - http://www.tandfonline.com/doi/full/10.1207/S15327914NC441_4 DB - PRIME DP - Unbound Medicine ER -