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[Comparison of characterization of hemagglutination and HA1 sequence of currently circulating strains of influenza A (H3N2) virus in Zhejiang province and in Japan].
Zhonghua Liu Xing Bing Xue Za Zhi. 2003 Jan; 24(1):15-8.ZL

Abstract

OBJECTIVE

To compare the characterization of hemagglutination and the sequence of HA1 region of the influenza A (H3N2) virus in Zhejiang province and Japan in recent years.

METHODS

Hemagglutinin antigenic analysis of influenza A (H3N2) viruses which were isolated in Zhejiang province was carried out and to compare their characterization of hemagglutination and the sequence of amino acids in HA1 region with the virus strains from Japan during the same period.

RESULTS

The antigenicity and the amino acid sequence in HA1 region of the virus strains prevalent in Zhejiang in recent years have changed to some extent. Most of the virus strains were lack of hemagglutination reaction to chicken red blood cell and became "O" phase virus strains. The amino acid sequence of HA1 region of the virus strains exhibited only 94.82% of its homology with that of A/Wuhan/359/95 strain. The virus strains of Japan in the same period showed similar characteristics.

CONCLUSION

HA1 gene variation of influenza A (H3N2) viruses was the main cause leading to the spread of influenza in the last years.

Authors+Show Affiliations

Institute of Virology, Zhejiang Provincial Center for Disease Prevention and Control, Hangzhou 310009, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

chi

PubMed ID

12678955

Citation

Lu, Yi-yu, et al. "[Comparison of Characterization of Hemagglutination and HA1 Sequence of Currently Circulating Strains of Influenza a (H3N2) Virus in Zhejiang Province and in Japan]." Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, vol. 24, no. 1, 2003, pp. 15-8.
Lu YY, Yan JY, Zhou M, et al. [Comparison of characterization of hemagglutination and HA1 sequence of currently circulating strains of influenza A (H3N2) virus in Zhejiang province and in Japan]. Zhonghua Liu Xing Bing Xue Za Zhi. 2003;24(1):15-8.
Lu, Y. Y., Yan, J. Y., Zhou, M., & Jiang, X. L. (2003). [Comparison of characterization of hemagglutination and HA1 sequence of currently circulating strains of influenza A (H3N2) virus in Zhejiang province and in Japan]. Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, 24(1), 15-8.
Lu YY, et al. [Comparison of Characterization of Hemagglutination and HA1 Sequence of Currently Circulating Strains of Influenza a (H3N2) Virus in Zhejiang Province and in Japan]. Zhonghua Liu Xing Bing Xue Za Zhi. 2003;24(1):15-8. PubMed PMID: 12678955.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Comparison of characterization of hemagglutination and HA1 sequence of currently circulating strains of influenza A (H3N2) virus in Zhejiang province and in Japan]. AU - Lu,Yi-yu, AU - Yan,Ju-ying, AU - Zhou,Min, AU - Jiang,Xiao-lu, PY - 2003/4/8/pubmed PY - 2004/11/4/medline PY - 2003/4/8/entrez SP - 15 EP - 8 JF - Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi JO - Zhonghua Liu Xing Bing Xue Za Zhi VL - 24 IS - 1 N2 - OBJECTIVE: To compare the characterization of hemagglutination and the sequence of HA1 region of the influenza A (H3N2) virus in Zhejiang province and Japan in recent years. METHODS: Hemagglutinin antigenic analysis of influenza A (H3N2) viruses which were isolated in Zhejiang province was carried out and to compare their characterization of hemagglutination and the sequence of amino acids in HA1 region with the virus strains from Japan during the same period. RESULTS: The antigenicity and the amino acid sequence in HA1 region of the virus strains prevalent in Zhejiang in recent years have changed to some extent. Most of the virus strains were lack of hemagglutination reaction to chicken red blood cell and became "O" phase virus strains. The amino acid sequence of HA1 region of the virus strains exhibited only 94.82% of its homology with that of A/Wuhan/359/95 strain. The virus strains of Japan in the same period showed similar characteristics. CONCLUSION: HA1 gene variation of influenza A (H3N2) viruses was the main cause leading to the spread of influenza in the last years. SN - 0254-6450 UR - https://www.unboundmedicine.com/medline/citation/12678955/[Comparison_of_characterization_of_hemagglutination_and_HA1_sequence_of_currently_circulating_strains_of_influenza_A__H3N2__virus_in_Zhejiang_province_and_in_Japan]_ L2 - https://medlineplus.gov/flu.html DB - PRIME DP - Unbound Medicine ER -