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Individual fatty acids influence cultured human liver cells differently when compared to plant oils.
Anticancer Res 2003 Jan-Feb; 23(1A):491-4AR

Abstract

Most work to date using fatty acids and cultured cells has concentrated on single fatty acids, yet cells in vivo are exposed to fatty acid combinations in the form of triacylglycerols and phosphoglycerides. We have quantitated the influence of the individual fatty acids that make up three plant oils, as well as the plant oils themselves, on the growth of normal and transformed human liver cell lines. The effects of the individual fatty acids were then combined in proportion to their concentration in each plant oil and compared to the effects of the intact oils. The oils initially induced synergistic effects with low concentrations, but with high concentrations competitive effects were shown, when compared to the combined effects of the individual fatty acids.

Authors+Show Affiliations

University of the Witwatersrand Medical School, 7 York Road, Parktown, 2193, South Africa.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12680255

Citation

Davidson, Bruce C., et al. "Individual Fatty Acids Influence Cultured Human Liver Cells Differently when Compared to Plant Oils." Anticancer Research, vol. 23, no. 1A, 2003, pp. 491-4.
Davidson BC, Girao LA, Giangregorio A. Individual fatty acids influence cultured human liver cells differently when compared to plant oils. Anticancer Res. 2003;23(1A):491-4.
Davidson, B. C., Girao, L. A., & Giangregorio, A. (2003). Individual fatty acids influence cultured human liver cells differently when compared to plant oils. Anticancer Research, 23(1A), pp. 491-4.
Davidson BC, Girao LA, Giangregorio A. Individual Fatty Acids Influence Cultured Human Liver Cells Differently when Compared to Plant Oils. Anticancer Res. 2003;23(1A):491-4. PubMed PMID: 12680255.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Individual fatty acids influence cultured human liver cells differently when compared to plant oils. AU - Davidson,Bruce C, AU - Girao,Luis A F, AU - Giangregorio,Alfredo, PY - 2003/4/12/pubmed PY - 2003/5/2/medline PY - 2003/4/12/entrez SP - 491 EP - 4 JF - Anticancer research JO - Anticancer Res. VL - 23 IS - 1A N2 - Most work to date using fatty acids and cultured cells has concentrated on single fatty acids, yet cells in vivo are exposed to fatty acid combinations in the form of triacylglycerols and phosphoglycerides. We have quantitated the influence of the individual fatty acids that make up three plant oils, as well as the plant oils themselves, on the growth of normal and transformed human liver cell lines. The effects of the individual fatty acids were then combined in proportion to their concentration in each plant oil and compared to the effects of the intact oils. The oils initially induced synergistic effects with low concentrations, but with high concentrations competitive effects were shown, when compared to the combined effects of the individual fatty acids. SN - 0250-7005 UR - https://www.unboundmedicine.com/medline/citation/12680255/Individual_fatty_acids_influence_cultured_human_liver_cells_differently_when_compared_to_plant_oils_ DB - PRIME DP - Unbound Medicine ER -