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How gluten-free is gluten-free, and what does this mean to coeliac patients?
Eur J Gastroenterol Hepatol. 2003 May; 15(5):461-3.EJ

Abstract

A gluten-free diet is the cornerstone treatment of coeliac disease. Until now, it is not known conclusively whether trace amounts of gluten might be allowed in the diet, as suggested by Codex Alimentarius. Gluten-free foods intended for dietary use can now be analysed reliably for residual gluten by the new R5 enzyme-linked immunosorbent assay (ELISA) system. Some major problems of gluten analysis (sensitivity, specificity, reproducibility) can be solved by the new method. Therefore, the information given by the new test system is relevant and superior to earlier methods. Further clinical studies using small dose challenges and dietary records including gluten analysis are necessary until a more meaningful discussion on standards for gluten-free foods can be started.

Authors+Show Affiliations

Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital of Leipzig, Germany. mothes@medizin.uni-leipzig.deNo affiliation info available

Pub Type(s)

Comment
Journal Article

Language

eng

PubMed ID

12702900

Citation

Mothes, Thomas, and Martin Stern. "How Gluten-free Is Gluten-free, and what Does This Mean to Coeliac Patients?" European Journal of Gastroenterology & Hepatology, vol. 15, no. 5, 2003, pp. 461-3.
Mothes T, Stern M. How gluten-free is gluten-free, and what does this mean to coeliac patients? Eur J Gastroenterol Hepatol. 2003;15(5):461-3.
Mothes, T., & Stern, M. (2003). How gluten-free is gluten-free, and what does this mean to coeliac patients? European Journal of Gastroenterology & Hepatology, 15(5), 461-3.
Mothes T, Stern M. How Gluten-free Is Gluten-free, and what Does This Mean to Coeliac Patients. Eur J Gastroenterol Hepatol. 2003;15(5):461-3. PubMed PMID: 12702900.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - How gluten-free is gluten-free, and what does this mean to coeliac patients? AU - Mothes,Thomas, AU - Stern,Martin, PY - 2003/4/19/pubmed PY - 2003/7/15/medline PY - 2003/4/19/entrez SP - 461 EP - 3 JF - European journal of gastroenterology & hepatology JO - Eur J Gastroenterol Hepatol VL - 15 IS - 5 N2 - A gluten-free diet is the cornerstone treatment of coeliac disease. Until now, it is not known conclusively whether trace amounts of gluten might be allowed in the diet, as suggested by Codex Alimentarius. Gluten-free foods intended for dietary use can now be analysed reliably for residual gluten by the new R5 enzyme-linked immunosorbent assay (ELISA) system. Some major problems of gluten analysis (sensitivity, specificity, reproducibility) can be solved by the new method. Therefore, the information given by the new test system is relevant and superior to earlier methods. Further clinical studies using small dose challenges and dietary records including gluten analysis are necessary until a more meaningful discussion on standards for gluten-free foods can be started. SN - 0954-691X UR - https://www.unboundmedicine.com/medline/citation/12702900/How_gluten_free_is_gluten_free_and_what_does_this_mean_to_coeliac_patients L2 - https://doi.org/10.1097/01.meg.0000059124.68845.8c DB - PRIME DP - Unbound Medicine ER -