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The effect of intranasal desmopressin on nocturnal waking in urination in multiple system atrophy patients with nocturnal polyuria.
Clin Auton Res. 2003 Apr; 13(2):106-8.CA

Abstract

Nocturnal waking in urination (nocturia) is a common feature in patients with multiple system atrophy (MSA). Degeneration of arginine vasopressin (AVP) neurons in the suprachiasmatic nucleus in this disorder may lead to nocturnal polyuria, which has been treated with intramuscular desmopressin. We also prescribed 5 microg of intranasal desmopressin once a night in 3 MSA patients, who had nocturnal polyuria with abnormal circadian rhythm of the plasma AVP. During the treatment, all patients showed an improvement in their nocturia without serious adverse effects.

Authors+Show Affiliations

Neurology Department, Chiba University, 1-8-1 Inohana Chuo-Ku, Chiba 260-8670, Japan. sakaki@med.m.chiba-u.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12720096

Citation

Sakakibara, Ryuji, et al. "The Effect of Intranasal Desmopressin On Nocturnal Waking in Urination in Multiple System Atrophy Patients With Nocturnal Polyuria." Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society, vol. 13, no. 2, 2003, pp. 106-8.
Sakakibara R, Matsuda S, Uchiyama T, et al. The effect of intranasal desmopressin on nocturnal waking in urination in multiple system atrophy patients with nocturnal polyuria. Clin Auton Res. 2003;13(2):106-8.
Sakakibara, R., Matsuda, S., Uchiyama, T., Yoshiyama, M., Yamanishi, T., & Hattori, T. (2003). The effect of intranasal desmopressin on nocturnal waking in urination in multiple system atrophy patients with nocturnal polyuria. Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society, 13(2), 106-8.
Sakakibara R, et al. The Effect of Intranasal Desmopressin On Nocturnal Waking in Urination in Multiple System Atrophy Patients With Nocturnal Polyuria. Clin Auton Res. 2003;13(2):106-8. PubMed PMID: 12720096.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effect of intranasal desmopressin on nocturnal waking in urination in multiple system atrophy patients with nocturnal polyuria. AU - Sakakibara,Ryuji, AU - Matsuda,Shinji, AU - Uchiyama,Tomoyuki, AU - Yoshiyama,Mitsuharu, AU - Yamanishi,Tomonori, AU - Hattori,Takamichi, PY - 2003/4/30/pubmed PY - 2004/1/17/medline PY - 2003/4/30/entrez SP - 106 EP - 8 JF - Clinical autonomic research : official journal of the Clinical Autonomic Research Society JO - Clin Auton Res VL - 13 IS - 2 N2 - Nocturnal waking in urination (nocturia) is a common feature in patients with multiple system atrophy (MSA). Degeneration of arginine vasopressin (AVP) neurons in the suprachiasmatic nucleus in this disorder may lead to nocturnal polyuria, which has been treated with intramuscular desmopressin. We also prescribed 5 microg of intranasal desmopressin once a night in 3 MSA patients, who had nocturnal polyuria with abnormal circadian rhythm of the plasma AVP. During the treatment, all patients showed an improvement in their nocturia without serious adverse effects. SN - 0959-9851 UR - https://www.unboundmedicine.com/medline/citation/12720096/The_effect_of_intranasal_desmopressin_on_nocturnal_waking_in_urination_in_multiple_system_atrophy_patients_with_nocturnal_polyuria_ L2 - http://dx.doi.org/10.1007/s10286-003-0052-3 DB - PRIME DP - Unbound Medicine ER -