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Diet and asthma: has the role of dietary lipids been overlooked in the management of asthma?
Ann Allergy Asthma Immunol 2003; 90(4):371-7; quiz 377-8, 421AA

Abstract

OBJECTIVE

This article discusses the role of diet in the management of asthma. Readers will gain an understanding of how evolution of the western diet has contributed to increased asthma prevalence and how dietary modification that includes management of dietary lipids may reduce symptoms of asthma.

DATA SOURCES

Relevant studies published in English were reviewed.

STUDY SELECTION

Medline search to identify peer-reviewed abstracts and journal articles.

RESULTS

Asthma and obesity, which often occur together, have increased in prevalence in recent years. Studies suggest adaption of a western diet has not only contributed to obesity, but that increased intake of specific nutrients can cause changes in the frequency and severity of asthma. Increased asthma prevalence has also been proposed to arise from increased exposure to diesel particles or lack of exposure to infectious agents or endotoxins during childhood, generating a biased Th2 immune response, and increased cytokine and leukotriene production. Antagonists directed against these pro-inflammatory mediators include anticytokines and antileukotrienes. A reduction in the levels of inflammatory mediators associated with asthma has also been seen with dietary interventions, such as the administration of oils containing gamma-linolenic acid and eicosapentaenoic acid.

CONCLUSIONS

Evidence suggests elevated body mass index and dietary patterns, especially intake of dietary lipids, contribute to symptoms of asthma. Dietary modification may help patients manage their asthma as well as contribute to their overall health.

Authors+Show Affiliations

University of California-Los Angeles, Los Angeles, California, USA. calallergy@dnamail.comNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

12722956

Citation

Spector, Sheldon L., and Marc E. Surette. "Diet and Asthma: Has the Role of Dietary Lipids Been Overlooked in the Management of Asthma?" Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology, vol. 90, no. 4, 2003, pp. 371-7; quiz 377-8, 421.
Spector SL, Surette ME. Diet and asthma: has the role of dietary lipids been overlooked in the management of asthma? Ann Allergy Asthma Immunol. 2003;90(4):371-7; quiz 377-8, 421.
Spector, S. L., & Surette, M. E. (2003). Diet and asthma: has the role of dietary lipids been overlooked in the management of asthma? Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology, 90(4), pp. 371-7; quiz 377-8, 421.
Spector SL, Surette ME. Diet and Asthma: Has the Role of Dietary Lipids Been Overlooked in the Management of Asthma. Ann Allergy Asthma Immunol. 2003;90(4):371-7; quiz 377-8, 421. PubMed PMID: 12722956.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diet and asthma: has the role of dietary lipids been overlooked in the management of asthma? AU - Spector,Sheldon L, AU - Surette,Marc E, PY - 2003/5/2/pubmed PY - 2003/5/29/medline PY - 2003/5/2/entrez SP - 371-7; quiz 377-8, 421 JF - Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology JO - Ann. Allergy Asthma Immunol. VL - 90 IS - 4 N2 - OBJECTIVE: This article discusses the role of diet in the management of asthma. Readers will gain an understanding of how evolution of the western diet has contributed to increased asthma prevalence and how dietary modification that includes management of dietary lipids may reduce symptoms of asthma. DATA SOURCES: Relevant studies published in English were reviewed. STUDY SELECTION: Medline search to identify peer-reviewed abstracts and journal articles. RESULTS: Asthma and obesity, which often occur together, have increased in prevalence in recent years. Studies suggest adaption of a western diet has not only contributed to obesity, but that increased intake of specific nutrients can cause changes in the frequency and severity of asthma. Increased asthma prevalence has also been proposed to arise from increased exposure to diesel particles or lack of exposure to infectious agents or endotoxins during childhood, generating a biased Th2 immune response, and increased cytokine and leukotriene production. Antagonists directed against these pro-inflammatory mediators include anticytokines and antileukotrienes. A reduction in the levels of inflammatory mediators associated with asthma has also been seen with dietary interventions, such as the administration of oils containing gamma-linolenic acid and eicosapentaenoic acid. CONCLUSIONS: Evidence suggests elevated body mass index and dietary patterns, especially intake of dietary lipids, contribute to symptoms of asthma. Dietary modification may help patients manage their asthma as well as contribute to their overall health. SN - 1081-1206 UR - https://www.unboundmedicine.com/medline/citation/12722956/Diet_and_asthma:_has_the_role_of_dietary_lipids_been_overlooked_in_the_management_of_asthma L2 - https://linkinghub.elsevier.com/retrieve/pii/S1081-1206(10)61817-0 DB - PRIME DP - Unbound Medicine ER -