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Kefir improves lactose digestion and tolerance in adults with lactose maldigestion.
J Am Diet Assoc. 2003 May; 103(5):582-7.JA

Abstract

OBJECTIVE

Kefir is a fermented milk beverage that contains different cultures than yogurt. The objective of this study was to determine whether kefir improves lactose digestion and tolerance in adults with lactose maldigestion.

DESIGN

Randomized block design.

SUBJECTS

Fifteen healthy, free-living adults with lactose maldigestion.

MAIN OUTCOME MEASURES

Breath hydrogen excretion and lactose intolerance symptoms were monitored hourly for 8 hours after each test meal.

INTERVENTION

Subjects were fed test meals consisting of 20 g lactose portions of milk (2% reduced fat), plain and raspberry flavored kefir, and plain and raspberry flavored yogurt, each following an overnight (12 hour) fast.

STATISTICAL ANALYSIS

Mixed model ANOVA was performed on raw or transformed data, followed by Tukey HSD post hoc tests (when appropriate). Significance was defined as P<.05.

RESULTS

The breath hydrogen area under the curve (AUC) for milk (224+/-39 ppm x h) was significantly greater than for the plain yogurt (76+/-14 ppm x h, P<.001), the plain kefir (87+/-37 ppm x h, P<.001), and the flavored yogurt (76+/-14 ppm x h, P=.005). The flavored kefir had an intermediate response (156+/-26 ppm x h). The yogurts and kefirs all similarly reduced the perceived severity of flatulence by 54% to 71% relative to milk. Abdominal pain and diarrhea symptoms were negligible among the five treatments.

APPLICATIONS/CONCLUSION

Because kefir improved lactose digestion and tolerance in this study, its use may be another potential strategy for overcoming lactose intolerance. Further studies of other types of kefir for improving lactose digestion are warranted.

Authors+Show Affiliations

Medical Dietetics Division, School of Allied Medical Professions, The Ohio State University, Columbus 43210-1234, USA. Hertzler.4@osu.eduNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12728216

Citation

Hertzler, Steven R., and Shannon M. Clancy. "Kefir Improves Lactose Digestion and Tolerance in Adults With Lactose Maldigestion." Journal of the American Dietetic Association, vol. 103, no. 5, 2003, pp. 582-7.
Hertzler SR, Clancy SM. Kefir improves lactose digestion and tolerance in adults with lactose maldigestion. J Am Diet Assoc. 2003;103(5):582-7.
Hertzler, S. R., & Clancy, S. M. (2003). Kefir improves lactose digestion and tolerance in adults with lactose maldigestion. Journal of the American Dietetic Association, 103(5), 582-7.
Hertzler SR, Clancy SM. Kefir Improves Lactose Digestion and Tolerance in Adults With Lactose Maldigestion. J Am Diet Assoc. 2003;103(5):582-7. PubMed PMID: 12728216.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Kefir improves lactose digestion and tolerance in adults with lactose maldigestion. AU - Hertzler,Steven R, AU - Clancy,Shannon M, PY - 2003/5/3/pubmed PY - 2003/5/22/medline PY - 2003/5/3/entrez SP - 582 EP - 7 JF - Journal of the American Dietetic Association JO - J Am Diet Assoc VL - 103 IS - 5 N2 - OBJECTIVE: Kefir is a fermented milk beverage that contains different cultures than yogurt. The objective of this study was to determine whether kefir improves lactose digestion and tolerance in adults with lactose maldigestion. DESIGN: Randomized block design. SUBJECTS: Fifteen healthy, free-living adults with lactose maldigestion. MAIN OUTCOME MEASURES: Breath hydrogen excretion and lactose intolerance symptoms were monitored hourly for 8 hours after each test meal. INTERVENTION: Subjects were fed test meals consisting of 20 g lactose portions of milk (2% reduced fat), plain and raspberry flavored kefir, and plain and raspberry flavored yogurt, each following an overnight (12 hour) fast. STATISTICAL ANALYSIS: Mixed model ANOVA was performed on raw or transformed data, followed by Tukey HSD post hoc tests (when appropriate). Significance was defined as P<.05. RESULTS: The breath hydrogen area under the curve (AUC) for milk (224+/-39 ppm x h) was significantly greater than for the plain yogurt (76+/-14 ppm x h, P<.001), the plain kefir (87+/-37 ppm x h, P<.001), and the flavored yogurt (76+/-14 ppm x h, P=.005). The flavored kefir had an intermediate response (156+/-26 ppm x h). The yogurts and kefirs all similarly reduced the perceived severity of flatulence by 54% to 71% relative to milk. Abdominal pain and diarrhea symptoms were negligible among the five treatments. APPLICATIONS/CONCLUSION: Because kefir improved lactose digestion and tolerance in this study, its use may be another potential strategy for overcoming lactose intolerance. Further studies of other types of kefir for improving lactose digestion are warranted. SN - 0002-8223 UR - https://www.unboundmedicine.com/medline/citation/12728216/Kefir_improves_lactose_digestion_and_tolerance_in_adults_with_lactose_maldigestion_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002822303002074 DB - PRIME DP - Unbound Medicine ER -