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[The effect of intrathecal fentanyl added to hyperbaric bupivacaine for caesarean section].
Masui. 2003 Apr; 52(4):378-82.M

Abstract

BACKGROUND

Management of cesarean section with spinal anesthesia is often accompanied with intraoperative nausea and pain. In a randomized controlled study, we explored the effect of intrathecal fentanyl on the characteristics of subarachnoid block in patients undergoing cesarean section.

METHODS

Twenty-four healthy parturients scheduled for elective Cesarean section were allocated to receive either fentanyl 0.3 ml (15 micrograms) or 0.9% saline 0.3 ml added to 0.5% hyperbaric bupivacaine 2.0 ml given intrathecally in the right decubitus position (n = 12 in each group). Level of sensory blockade was evaluated with cold test and intraoperative use of antiemetics and analgesics was recorded.

RESULTS

The maximum level of sensory blockade was significantly higher in the fentanyl group as compared with the control group (P = 0.019). Use of intraoperative antiemetics was significantly less often in the fentanyl group (P = 0.007). The required amount of intraoperative analgesics was smaller in the fentanyl group, although the difference was not significant (P = 0.11). No remarkable side effects, such as respiratory depression and hypoxia were observed. Apgar scores in the newborn were similar.

CONCLUSION

Addition of intrathecal fentanyl to hyperbaric bupivacaine in parturients undergoing cesarean section improved quality of anesthesia without producing significant side effects.

Authors+Show Affiliations

Department of Anesthesiology, Tokyo University School of Medicine, Tokyo 113-8655.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
English Abstract
Journal Article
Randomized Controlled Trial

Language

jpn

PubMed ID

12728487

Citation

Obara, Mizuki, et al. "[The Effect of Intrathecal Fentanyl Added to Hyperbaric Bupivacaine for Caesarean Section]." Masui. the Japanese Journal of Anesthesiology, vol. 52, no. 4, 2003, pp. 378-82.
Obara M, Sawamura S, Satoh Y, et al. [The effect of intrathecal fentanyl added to hyperbaric bupivacaine for caesarean section]. Masui. 2003;52(4):378-82.
Obara, M., Sawamura, S., Satoh, Y., Chinzei, M., Sekiyama, H., Tamai, H., Yamamoto, H., & Hanaoka, K. (2003). [The effect of intrathecal fentanyl added to hyperbaric bupivacaine for caesarean section]. Masui. the Japanese Journal of Anesthesiology, 52(4), 378-82.
Obara M, et al. [The Effect of Intrathecal Fentanyl Added to Hyperbaric Bupivacaine for Caesarean Section]. Masui. 2003;52(4):378-82. PubMed PMID: 12728487.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The effect of intrathecal fentanyl added to hyperbaric bupivacaine for caesarean section]. AU - Obara,Mizuki, AU - Sawamura,Shigehito, AU - Satoh,Yoshiaki, AU - Chinzei,Mieko, AU - Sekiyama,Hiroshi, AU - Tamai,Hisayoshi, AU - Yamamoto,Hirotoshi, AU - Hanaoka,Kazuo, PY - 2003/5/6/pubmed PY - 2003/8/9/medline PY - 2003/5/6/entrez SP - 378 EP - 82 JF - Masui. The Japanese journal of anesthesiology JO - Masui VL - 52 IS - 4 N2 - BACKGROUND: Management of cesarean section with spinal anesthesia is often accompanied with intraoperative nausea and pain. In a randomized controlled study, we explored the effect of intrathecal fentanyl on the characteristics of subarachnoid block in patients undergoing cesarean section. METHODS: Twenty-four healthy parturients scheduled for elective Cesarean section were allocated to receive either fentanyl 0.3 ml (15 micrograms) or 0.9% saline 0.3 ml added to 0.5% hyperbaric bupivacaine 2.0 ml given intrathecally in the right decubitus position (n = 12 in each group). Level of sensory blockade was evaluated with cold test and intraoperative use of antiemetics and analgesics was recorded. RESULTS: The maximum level of sensory blockade was significantly higher in the fentanyl group as compared with the control group (P = 0.019). Use of intraoperative antiemetics was significantly less often in the fentanyl group (P = 0.007). The required amount of intraoperative analgesics was smaller in the fentanyl group, although the difference was not significant (P = 0.11). No remarkable side effects, such as respiratory depression and hypoxia were observed. Apgar scores in the newborn were similar. CONCLUSION: Addition of intrathecal fentanyl to hyperbaric bupivacaine in parturients undergoing cesarean section improved quality of anesthesia without producing significant side effects. SN - 0021-4892 UR - https://www.unboundmedicine.com/medline/citation/12728487/[The_effect_of_intrathecal_fentanyl_added_to_hyperbaric_bupivacaine_for_caesarean_section]_ L2 - https://medlineplus.gov/cesareansection.html DB - PRIME DP - Unbound Medicine ER -