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Symptoms associated with impaired gastric emptying of solids and liquids in functional dyspepsia.
Am J Gastroenterol. 2003 Apr; 98(4):783-8.AJ

Abstract

OBJECTIVE

The relationship between functional dyspepsia and delayed gastric emptying of solids or liquids is still unclear. The aim of the present study was to investigate in dyspeptic patients the prevalence of delayed gastric emptying for solids or for liquids and to investigate the relationship to the dyspepsia symptom pattern.

METHODS

In 392 and 330 patients with functional dyspepsia, the solid and liquid gastric emptying, respectively, was measured using breath tests, and the severity of eight dyspeptic symptoms was scored.

RESULTS

Gastric emptying of solids and liquids were delayed in 23% and 35% of the patients. Multivariate analysis showed that the presence of vomiting and postprandial fullness was associated with delayed solid emptying (OR 2.65, 95% CI = 1.62-4.35 and OR 3.08, 95% CI = 1.28-9.16, respectively). Postprandial fullness was also associated with the risk of delayed liquid emptying when symptom was present (OR 3.5, 95% CI = 1.57-8.68), relevant or severe (OR 2.504, 95% CI = 1.41-4.65), and severe (OR 2.214, 95% CI = 1.34-3.67). Severe early satiety was associated with the risk of delayed liquid emptying (OR 1.902, 95% CI = 1.90-3.30).

CONCLUSIONS

A subset of dyspeptic patients has delayed gastric emptying of solids or of liquids. Delayed gastric emptying of solids was constantly associated with postprandial fullness and with vomiting. Delayed emptying for liquids was also associated with postprandial fullness and with severe early satiety.

Authors+Show Affiliations

Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12738456

Citation

Sarnelli, Giovanni, et al. "Symptoms Associated With Impaired Gastric Emptying of Solids and Liquids in Functional Dyspepsia." The American Journal of Gastroenterology, vol. 98, no. 4, 2003, pp. 783-8.
Sarnelli G, Caenepeel P, Geypens B, et al. Symptoms associated with impaired gastric emptying of solids and liquids in functional dyspepsia. Am J Gastroenterol. 2003;98(4):783-8.
Sarnelli, G., Caenepeel, P., Geypens, B., Janssens, J., & Tack, J. (2003). Symptoms associated with impaired gastric emptying of solids and liquids in functional dyspepsia. The American Journal of Gastroenterology, 98(4), 783-8.
Sarnelli G, et al. Symptoms Associated With Impaired Gastric Emptying of Solids and Liquids in Functional Dyspepsia. Am J Gastroenterol. 2003;98(4):783-8. PubMed PMID: 12738456.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Symptoms associated with impaired gastric emptying of solids and liquids in functional dyspepsia. AU - Sarnelli,Giovanni, AU - Caenepeel,Philip, AU - Geypens,Benny, AU - Janssens,Jozef, AU - Tack,Jan, PY - 2003/5/10/pubmed PY - 2003/6/12/medline PY - 2003/5/10/entrez SP - 783 EP - 8 JF - The American journal of gastroenterology JO - Am J Gastroenterol VL - 98 IS - 4 N2 - OBJECTIVE: The relationship between functional dyspepsia and delayed gastric emptying of solids or liquids is still unclear. The aim of the present study was to investigate in dyspeptic patients the prevalence of delayed gastric emptying for solids or for liquids and to investigate the relationship to the dyspepsia symptom pattern. METHODS: In 392 and 330 patients with functional dyspepsia, the solid and liquid gastric emptying, respectively, was measured using breath tests, and the severity of eight dyspeptic symptoms was scored. RESULTS: Gastric emptying of solids and liquids were delayed in 23% and 35% of the patients. Multivariate analysis showed that the presence of vomiting and postprandial fullness was associated with delayed solid emptying (OR 2.65, 95% CI = 1.62-4.35 and OR 3.08, 95% CI = 1.28-9.16, respectively). Postprandial fullness was also associated with the risk of delayed liquid emptying when symptom was present (OR 3.5, 95% CI = 1.57-8.68), relevant or severe (OR 2.504, 95% CI = 1.41-4.65), and severe (OR 2.214, 95% CI = 1.34-3.67). Severe early satiety was associated with the risk of delayed liquid emptying (OR 1.902, 95% CI = 1.90-3.30). CONCLUSIONS: A subset of dyspeptic patients has delayed gastric emptying of solids or of liquids. Delayed gastric emptying of solids was constantly associated with postprandial fullness and with vomiting. Delayed emptying for liquids was also associated with postprandial fullness and with severe early satiety. SN - 0002-9270 UR - https://www.unboundmedicine.com/medline/citation/12738456/Symptoms_associated_with_impaired_gastric_emptying_of_solids_and_liquids_in_functional_dyspepsia_ DB - PRIME DP - Unbound Medicine ER -