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Effect of twice weekly versus daily iron treatment in Turkish children with iron deficiency anemia.
Pediatr Hematol Oncol 2003; 20(4):319-26PH

Abstract

This study was designed to propose a more practical, effective, safer, inexpensive, and manageable alternative treatment of iron deficiency anemia (IDA) for the developing countries. The study involves 94 children between the ages of 5 months and 6 years who had been seen in the authors' hospital and diagnosed as having iron deficiency anemia. Ninety-four children with IDA were randomly divided into two groups: 48 children comprised the first group, which was administered conventional treatment, and 46 children comprised the second group, which was administered intermittent treatment involving iron administration 2 days a week. Twenty-three children whose age and gender distribution were compatible with the other groups were included in the study as the control group. Both groups were reevaluated for their initial hematologic parameters at the end of the treatment. When the parameters of both groups were compared with the parameters of the control group after the treatment, there were no differences between hemoglobin, hematocrit, red blood cell, mean corpuscular volume, mean corpuscular hemoglobin concentration, serum iron, and ferritin levels of conventional and intermittent treatment groups. With respect to certain parameters, such as red cell distribution, serum iron binding capacity, transferrin saturation, transferrin receptor, and transferrin receptor/log ferritin, however, intermittent treatment was superior to the conventional treatment method (p <.05). In IDA, when a conventional treatment method or an intermittent treatment method is used, there are no differences between the hematological parameters. In fact, the intermittent treatment method has been found to be superior in many parameters.

Authors+Show Affiliations

Dr. Sami Ulus Children's Hospital, Ankara, Turkey.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

12746164

Citation

Tavil, Betül, et al. "Effect of Twice Weekly Versus Daily Iron Treatment in Turkish Children With Iron Deficiency Anemia." Pediatric Hematology and Oncology, vol. 20, no. 4, 2003, pp. 319-26.
Tavil B, Sipahi T, Gökçe H, et al. Effect of twice weekly versus daily iron treatment in Turkish children with iron deficiency anemia. Pediatr Hematol Oncol. 2003;20(4):319-26.
Tavil, B., Sipahi, T., Gökçe, H., & Akar, N. (2003). Effect of twice weekly versus daily iron treatment in Turkish children with iron deficiency anemia. Pediatric Hematology and Oncology, 20(4), pp. 319-26.
Tavil B, et al. Effect of Twice Weekly Versus Daily Iron Treatment in Turkish Children With Iron Deficiency Anemia. Pediatr Hematol Oncol. 2003;20(4):319-26. PubMed PMID: 12746164.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of twice weekly versus daily iron treatment in Turkish children with iron deficiency anemia. AU - Tavil,Betül, AU - Sipahi,Tansu, AU - Gökçe,Hafize, AU - Akar,Nejat, PY - 2003/5/15/pubmed PY - 2004/2/3/medline PY - 2003/5/15/entrez SP - 319 EP - 26 JF - Pediatric hematology and oncology JO - Pediatr Hematol Oncol VL - 20 IS - 4 N2 - This study was designed to propose a more practical, effective, safer, inexpensive, and manageable alternative treatment of iron deficiency anemia (IDA) for the developing countries. The study involves 94 children between the ages of 5 months and 6 years who had been seen in the authors' hospital and diagnosed as having iron deficiency anemia. Ninety-four children with IDA were randomly divided into two groups: 48 children comprised the first group, which was administered conventional treatment, and 46 children comprised the second group, which was administered intermittent treatment involving iron administration 2 days a week. Twenty-three children whose age and gender distribution were compatible with the other groups were included in the study as the control group. Both groups were reevaluated for their initial hematologic parameters at the end of the treatment. When the parameters of both groups were compared with the parameters of the control group after the treatment, there were no differences between hemoglobin, hematocrit, red blood cell, mean corpuscular volume, mean corpuscular hemoglobin concentration, serum iron, and ferritin levels of conventional and intermittent treatment groups. With respect to certain parameters, such as red cell distribution, serum iron binding capacity, transferrin saturation, transferrin receptor, and transferrin receptor/log ferritin, however, intermittent treatment was superior to the conventional treatment method (p <.05). In IDA, when a conventional treatment method or an intermittent treatment method is used, there are no differences between the hematological parameters. In fact, the intermittent treatment method has been found to be superior in many parameters. SN - 0888-0018 UR - https://www.unboundmedicine.com/medline/citation/12746164/Effect_of_twice_weekly_versus_daily_iron_treatment_in_Turkish_children_with_iron_deficiency_anemia_ L2 - http://www.diseaseinfosearch.org/result/3873 DB - PRIME DP - Unbound Medicine ER -