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Tomatoes, lycopene and prostate cancer: a clinician's guide for counseling those at risk for prostate cancer.
World J Urol. 2003 May; 21(1):9-14.WJ

Abstract

Prostate cancer has become a major public health issue and the search for etiologic risk factors and the development of chemopreventive agents has gained momentum over the last decade. An important epidemiologic finding has been the association between the consumption of tomato products and a lower risk of prostate cancer. Several investigators have proposed that lycopene, a carotenoid consumed largely from tomato products, may be the component responsible for lowering the risk of prostate cancer. Laboratory and clinical studies have been initiated with the goal of assessing the ability of pure lycopene to serve as a chemopreventive agent for prostate cancer. The focus on lycopene should continue, and an improved understanding of lycopene absorption, distribution, role in antioxidant reactions, and metabolism is critical in the quest to elucidate mechanisms whereby this compound may possibly reduce prostate cancer risk.

Authors+Show Affiliations

Division of Urology, Department of Surgery, Ohio State University College of Medicine and Public Health, 4841 UHC, 456 West 10th Avenue, Columbus, OH 43210, USA. pohar-1@medctr.osu.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

12756488

Citation

Pohar, Kamal S., et al. "Tomatoes, Lycopene and Prostate Cancer: a Clinician's Guide for Counseling Those at Risk for Prostate Cancer." World Journal of Urology, vol. 21, no. 1, 2003, pp. 9-14.
Pohar KS, Gong MC, Bahnson R, et al. Tomatoes, lycopene and prostate cancer: a clinician's guide for counseling those at risk for prostate cancer. World J Urol. 2003;21(1):9-14.
Pohar, K. S., Gong, M. C., Bahnson, R., Miller, E. C., & Clinton, S. K. (2003). Tomatoes, lycopene and prostate cancer: a clinician's guide for counseling those at risk for prostate cancer. World Journal of Urology, 21(1), 9-14.
Pohar KS, et al. Tomatoes, Lycopene and Prostate Cancer: a Clinician's Guide for Counseling Those at Risk for Prostate Cancer. World J Urol. 2003;21(1):9-14. PubMed PMID: 12756488.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Tomatoes, lycopene and prostate cancer: a clinician's guide for counseling those at risk for prostate cancer. AU - Pohar,Kamal S, AU - Gong,Michael C, AU - Bahnson,Robert, AU - Miller,Elizabeth C, AU - Clinton,Steven K, Y1 - 2003/03/22/ PY - 2002/12/10/received PY - 2002/12/15/accepted PY - 2003/5/21/pubmed PY - 2003/10/15/medline PY - 2003/5/21/entrez SP - 9 EP - 14 JF - World journal of urology JO - World J Urol VL - 21 IS - 1 N2 - Prostate cancer has become a major public health issue and the search for etiologic risk factors and the development of chemopreventive agents has gained momentum over the last decade. An important epidemiologic finding has been the association between the consumption of tomato products and a lower risk of prostate cancer. Several investigators have proposed that lycopene, a carotenoid consumed largely from tomato products, may be the component responsible for lowering the risk of prostate cancer. Laboratory and clinical studies have been initiated with the goal of assessing the ability of pure lycopene to serve as a chemopreventive agent for prostate cancer. The focus on lycopene should continue, and an improved understanding of lycopene absorption, distribution, role in antioxidant reactions, and metabolism is critical in the quest to elucidate mechanisms whereby this compound may possibly reduce prostate cancer risk. SN - 0724-4983 UR - https://www.unboundmedicine.com/medline/citation/12756488/Tomatoes_lycopene_and_prostate_cancer:_a_clinician's_guide_for_counseling_those_at_risk_for_prostate_cancer_ L2 - https://dx.doi.org/10.1007/s00345-003-0318-3 DB - PRIME DP - Unbound Medicine ER -