Tags

Type your tag names separated by a space and hit enter

Gender differences in cardiovascular and hypothalamic-pituitary-adrenal axis responses to psychological stress in healthy older adult men and women.
Stress. 2003 Jun; 6(2):133-40.S

Abstract

Gender differences in the neuroendocrine and cardiovascular response to psychological stress may contribute to the gender differences in the prevalence of diseases associated with hypothalamic-pituitary-adrenal (HPA) axis reactivity such as cardiovascular disease (CVD), diabetes and hypertension. We measured plasma ACTH, cortisol, heart rate (HR), and blood pressure (BP) responses in 8 men and 8 women (55-75 years) exposed to the Matt Stress Reactivity Protocol (MSRP), a psychological challenge. The MSRP elicited significant increases in HR, systolic-, and diastolic BP, ACTH and cortisol (all p<0.01). Men had significantly greater cortisol and diastolic BP responses compared to women (p<0.05). Additionally, a positive correlation between the ACTH and cortisol responses was only found in the males (r=0.71, p<0.05). There were no group differences in HR, systolic BP, or ACTH responses. We conclude, that among older adults, men respond to psychological stress with greater increases in cortisol, compared to women. This greater activation of the HPA axis could translate into an elevated risk for CVD, diabetes and hypertension and may be related to the higher prevalence of these diseases in males. Gender differences in brain structures and/or cognitive processes may be responsible for these sexually dimorphic stress responses.

Authors+Show Affiliations

Neuroendocrine Laboratory, Department of Kinesiology, Arizona State University, Tempe 85287-0404, USA. tinna@asu.eduNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

12775333

Citation

Traustadóttir, T, et al. "Gender Differences in Cardiovascular and Hypothalamic-pituitary-adrenal Axis Responses to Psychological Stress in Healthy Older Adult Men and Women." Stress (Amsterdam, Netherlands), vol. 6, no. 2, 2003, pp. 133-40.
Traustadóttir T, Bosch PR, Matt KS. Gender differences in cardiovascular and hypothalamic-pituitary-adrenal axis responses to psychological stress in healthy older adult men and women. Stress. 2003;6(2):133-40.
Traustadóttir, T., Bosch, P. R., & Matt, K. S. (2003). Gender differences in cardiovascular and hypothalamic-pituitary-adrenal axis responses to psychological stress in healthy older adult men and women. Stress (Amsterdam, Netherlands), 6(2), 133-40.
Traustadóttir T, Bosch PR, Matt KS. Gender Differences in Cardiovascular and Hypothalamic-pituitary-adrenal Axis Responses to Psychological Stress in Healthy Older Adult Men and Women. Stress. 2003;6(2):133-40. PubMed PMID: 12775333.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gender differences in cardiovascular and hypothalamic-pituitary-adrenal axis responses to psychological stress in healthy older adult men and women. AU - Traustadóttir,T, AU - Bosch,P R, AU - Matt,K S, PY - 2003/5/31/pubmed PY - 2003/8/7/medline PY - 2003/5/31/entrez SP - 133 EP - 40 JF - Stress (Amsterdam, Netherlands) JO - Stress VL - 6 IS - 2 N2 - Gender differences in the neuroendocrine and cardiovascular response to psychological stress may contribute to the gender differences in the prevalence of diseases associated with hypothalamic-pituitary-adrenal (HPA) axis reactivity such as cardiovascular disease (CVD), diabetes and hypertension. We measured plasma ACTH, cortisol, heart rate (HR), and blood pressure (BP) responses in 8 men and 8 women (55-75 years) exposed to the Matt Stress Reactivity Protocol (MSRP), a psychological challenge. The MSRP elicited significant increases in HR, systolic-, and diastolic BP, ACTH and cortisol (all p<0.01). Men had significantly greater cortisol and diastolic BP responses compared to women (p<0.05). Additionally, a positive correlation between the ACTH and cortisol responses was only found in the males (r=0.71, p<0.05). There were no group differences in HR, systolic BP, or ACTH responses. We conclude, that among older adults, men respond to psychological stress with greater increases in cortisol, compared to women. This greater activation of the HPA axis could translate into an elevated risk for CVD, diabetes and hypertension and may be related to the higher prevalence of these diseases in males. Gender differences in brain structures and/or cognitive processes may be responsible for these sexually dimorphic stress responses. SN - 1025-3890 UR - https://www.unboundmedicine.com/medline/citation/12775333/Gender_differences_in_cardiovascular_and_hypothalamic_pituitary_adrenal_axis_responses_to_psychological_stress_in_healthy_older_adult_men_and_women_ L2 - https://www.tandfonline.com/doi/full/10.1080/1025389031000111302 DB - PRIME DP - Unbound Medicine ER -