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Carvedilol: something else than a simple betablocker?
Eur Rev Med Pharmacol Sci. 2002 Nov-Dec; 6(6):115-26.ER

Abstract

Carvedilol is a cardiovascular drug of multifaceted therapeutic potential, with beta-blocker and vasodilatative activity. These actions confer to the above mentioned betablocker some beneficial properties on several processes involving cardiovascular system. Carvedilol provides haemodynamic, antiischemic, antiproliferative and antiarrhytmic benefits, for its antioxidant neurohumoral and electrophysiological effects. All these actions provide the basis for usefulness of the drug in the treatment of hypertension, coronary heart disease, and congestive heart failure. In this review we report the beneficial properties of Carvedilol and we analyze the rational clinical use of this betablocker taking special attention on recent clinical trial in heart failure where it appears an evidence supporting an important, favourable effect of the drug.

Authors+Show Affiliations

Institute of Clinical and Experimental Medicine, University of Siena.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

12776805

Citation

Palazzuoli, A, et al. "Carvedilol: Something Else Than a Simple Betablocker?" European Review for Medical and Pharmacological Sciences, vol. 6, no. 6, 2002, pp. 115-26.
Palazzuoli A, Calabria P, Verzuri MS, et al. Carvedilol: something else than a simple betablocker? Eur Rev Med Pharmacol Sci. 2002;6(6):115-26.
Palazzuoli, A., Calabria, P., Verzuri, M. S., & Auteri, A. (2002). Carvedilol: something else than a simple betablocker? European Review for Medical and Pharmacological Sciences, 6(6), 115-26.
Palazzuoli A, et al. Carvedilol: Something Else Than a Simple Betablocker. Eur Rev Med Pharmacol Sci. 2002 Nov-Dec;6(6):115-26. PubMed PMID: 12776805.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Carvedilol: something else than a simple betablocker? AU - Palazzuoli,A, AU - Calabria,P, AU - Verzuri,M S, AU - Auteri,A, PY - 2003/6/5/pubmed PY - 2003/6/19/medline PY - 2003/6/5/entrez SP - 115 EP - 26 JF - European review for medical and pharmacological sciences JO - Eur Rev Med Pharmacol Sci VL - 6 IS - 6 N2 - Carvedilol is a cardiovascular drug of multifaceted therapeutic potential, with beta-blocker and vasodilatative activity. These actions confer to the above mentioned betablocker some beneficial properties on several processes involving cardiovascular system. Carvedilol provides haemodynamic, antiischemic, antiproliferative and antiarrhytmic benefits, for its antioxidant neurohumoral and electrophysiological effects. All these actions provide the basis for usefulness of the drug in the treatment of hypertension, coronary heart disease, and congestive heart failure. In this review we report the beneficial properties of Carvedilol and we analyze the rational clinical use of this betablocker taking special attention on recent clinical trial in heart failure where it appears an evidence supporting an important, favourable effect of the drug. SN - 1128-3602 UR - https://www.unboundmedicine.com/medline/citation/12776805/Carvedilol:_something_else_than_a_simple_betablocker L2 - https://medlineplus.gov/bloodpressuremedicines.html DB - PRIME DP - Unbound Medicine ER -