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Leptospirosis in "Eco-Challenge" athletes, Malaysian Borneo, 2000.
Emerg Infect Dis. 2003 Jun; 9(6):702-7.EI

Abstract

Adventure travel is becoming more popular, increasing the likelihood of contact with unusual pathogens. We investigated an outbreak of leptospirosis in "Eco-Challenge" multisport race athletes to determine illness etiology and implement public health measures. Of 304 athletes, we contacted 189 (62%) from the United States and 26 other countries. Eighty (42%) athletes met our case definition. Twenty-nine (36%) case-patients were hospitalized; none died. Logistic regression showed swimming in the Segama River (relative risk [RR]=2.0; 95% confidence interval [CI]=1.3 to 3.1) to be an independent risk factor. Twenty-six (68%) of 38 case-patients tested positive for leptospiral antibodies. Taking doxycycline before or during the race was protective (RR=0.4, 95% CI=0.2 to 1.2) for the 20 athletes who reported using it. Increased adventure travel may lead to more frequent exposure to leptospires, and preexposure chemoprophylaxis for leptospirosis (200 mg oral doxycycline/week) may decrease illness risk. Efforts are needed to inform adventure travel participants of unique infections such as leptospirosis.

Authors+Show Affiliations

Division of Viral and Rickettsial Diseases, Mailstop A39, NCID, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. zea3@cdc.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12781010

Citation

Sejvar, James, et al. "Leptospirosis in "Eco-Challenge" Athletes, Malaysian Borneo, 2000." Emerging Infectious Diseases, vol. 9, no. 6, 2003, pp. 702-7.
Sejvar J, Bancroft E, Winthrop K, et al. Leptospirosis in "Eco-Challenge" athletes, Malaysian Borneo, 2000. Emerg Infect Dis. 2003;9(6):702-7.
Sejvar, J., Bancroft, E., Winthrop, K., Bettinger, J., Bajani, M., Bragg, S., Shutt, K., Kaiser, R., Marano, N., Popovic, T., Tappero, J., Ashford, D., Mascola, L., Vugia, D., Perkins, B., & Rosenstein, N. (2003). Leptospirosis in "Eco-Challenge" athletes, Malaysian Borneo, 2000. Emerging Infectious Diseases, 9(6), 702-7.
Sejvar J, et al. Leptospirosis in "Eco-Challenge" Athletes, Malaysian Borneo, 2000. Emerg Infect Dis. 2003;9(6):702-7. PubMed PMID: 12781010.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Leptospirosis in "Eco-Challenge" athletes, Malaysian Borneo, 2000. AU - Sejvar,James, AU - Bancroft,Elizabeth, AU - Winthrop,Kevin, AU - Bettinger,Julie, AU - Bajani,Mary, AU - Bragg,Sandra, AU - Shutt,Kathleen, AU - Kaiser,Robyn, AU - Marano,Nina, AU - Popovic,Tanja, AU - Tappero,Jordan, AU - Ashford,David, AU - Mascola,Laurene, AU - Vugia,Duc, AU - Perkins,Bradley, AU - Rosenstein,Nancy, AU - ,, PY - 2003/6/5/pubmed PY - 2003/9/11/medline PY - 2003/6/5/entrez SP - 702 EP - 7 JF - Emerging infectious diseases JO - Emerg Infect Dis VL - 9 IS - 6 N2 - Adventure travel is becoming more popular, increasing the likelihood of contact with unusual pathogens. We investigated an outbreak of leptospirosis in "Eco-Challenge" multisport race athletes to determine illness etiology and implement public health measures. Of 304 athletes, we contacted 189 (62%) from the United States and 26 other countries. Eighty (42%) athletes met our case definition. Twenty-nine (36%) case-patients were hospitalized; none died. Logistic regression showed swimming in the Segama River (relative risk [RR]=2.0; 95% confidence interval [CI]=1.3 to 3.1) to be an independent risk factor. Twenty-six (68%) of 38 case-patients tested positive for leptospiral antibodies. Taking doxycycline before or during the race was protective (RR=0.4, 95% CI=0.2 to 1.2) for the 20 athletes who reported using it. Increased adventure travel may lead to more frequent exposure to leptospires, and preexposure chemoprophylaxis for leptospirosis (200 mg oral doxycycline/week) may decrease illness risk. Efforts are needed to inform adventure travel participants of unique infections such as leptospirosis. SN - 1080-6040 UR - https://www.unboundmedicine.com/medline/citation/12781010/Leptospirosis_in_"Eco_Challenge"_athletes_Malaysian_Borneo_2000_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/12781010/ DB - PRIME DP - Unbound Medicine ER -