Tags

Type your tag names separated by a space and hit enter

Occupation and gastric cancer.

Abstract

Gastric cancer is a cause of significant morbidity and mortality. There are several risk factors, with occupation emerging as one of these. There is considerable evidence that occupations in coal and tin mining, metal processing, particularly steel and iron, and rubber manufacturing industries lead to an increased risk of gastric cancer. Other "dusty" occupations-for example, wood processing, or work in high temperature environments have also been implicated but the evidence is not strong. The mechanism of pathogenesis of gastric cancer is unclear and the identification of causative agents can be difficult. Dust is thought to be a contributor to the pathological process, but well known carcinogens such as N-nitroso compounds have been detected in some environments. Further research on responsible agents is necessary and screening for detection of precursor gastric cancer lesions at the workplace merits consideration.

Links

  • PMC Free PDF
  • PMC Free Full Text
  • FREE Publisher Full Text
  • Authors+Show Affiliations

    ,

    Gastrointestinal Research Unit, Leicester General Hospital Thessalonika, Greece. anitaaraj@aol.com

    ,

    Source

    Postgraduate medical journal 79:931 2003 May pg 252-8

    MeSH

    Chemical Industry
    Food Industry
    Humans
    Metallurgy
    Mining
    Occupational Diseases
    Occupations
    Risk Factors
    Stomach Neoplasms
    Transportation
    Wood

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    12782770

    Citation

    Raj, A, et al. "Occupation and Gastric Cancer." Postgraduate Medical Journal, vol. 79, no. 931, 2003, pp. 252-8.
    Raj A, Mayberry JF, Podas T. Occupation and gastric cancer. Postgrad Med J. 2003;79(931):252-8.
    Raj, A., Mayberry, J. F., & Podas, T. (2003). Occupation and gastric cancer. Postgraduate Medical Journal, 79(931), pp. 252-8.
    Raj A, Mayberry JF, Podas T. Occupation and Gastric Cancer. Postgrad Med J. 2003;79(931):252-8. PubMed PMID: 12782770.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Occupation and gastric cancer. AU - Raj,A, AU - Mayberry,J F, AU - Podas,T, PY - 2003/6/5/pubmed PY - 2003/7/15/medline PY - 2003/6/5/entrez SP - 252 EP - 8 JF - Postgraduate medical journal JO - Postgrad Med J VL - 79 IS - 931 N2 - Gastric cancer is a cause of significant morbidity and mortality. There are several risk factors, with occupation emerging as one of these. There is considerable evidence that occupations in coal and tin mining, metal processing, particularly steel and iron, and rubber manufacturing industries lead to an increased risk of gastric cancer. Other "dusty" occupations-for example, wood processing, or work in high temperature environments have also been implicated but the evidence is not strong. The mechanism of pathogenesis of gastric cancer is unclear and the identification of causative agents can be difficult. Dust is thought to be a contributor to the pathological process, but well known carcinogens such as N-nitroso compounds have been detected in some environments. Further research on responsible agents is necessary and screening for detection of precursor gastric cancer lesions at the workplace merits consideration. SN - 0032-5473 UR - https://www.unboundmedicine.com/medline/citation/12782770/full_citation L2 - http://pmj.bmj.com/cgi/pmidlookup?view=long&pmid=12782770 DB - PRIME DP - Unbound Medicine ER -