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Aerobic capacity and peripheral skeletal muscle function in coronary artery disease male patients.
Int J Sports Med. 2003 May; 24(4):258-63.IJ

Abstract

The aim of this study was to determine if the diminished aerobic capacity of coronary artery disease male (CAD) patients is accompanied by an impaired skeletal muscle function compared to healthy control subjects. Thirteen CAD patients and 9 healthy subjects performed both a maximal laboratory exercise testing and an assessment of the peripheral skeletal muscle function on an isokinetic apparatus. The cardiorespiratory and mechanical parameters were measured at ventilatory threshold and at maximal effort during a maximal exercise testing. The peripheral skeletal muscle function of the quadriceps was assessed from the maximal voluntary isometric force (MVIF) and from the static endurance time (SET) at an intensity of 50 % of the MVIF. The CAD patients showed a diminished aerobic capacity compared to healthy control subjects at maximal effort (maximal VO(2) uptake: p < 0.0001, maximal ventilation: p < 0.01; maximal heart rate: p < 0.0001, maximal power: p < 0.001) but also at VT (VO(2) uptake VT: p < 0.0001, Power VT: p < 0.001). No difference was found on the MVIF (p < 0.90) between the CAD patients and the control subjects whereas the SET was lower in the CAD patients (p < 0.01). The CAD patients had a lower aerobic capacity and an impaired skeletal muscle endurance compared to healthy subjects.

Authors+Show Affiliations

Gayda M
Laboratoire de recherche EA 3300 APS et Conduites Motrices: Adaptations et Réadaptations, Faculté des Sciences du Sport, Université de Picardie Jules Verne, 80025 Amiens Cedex 1, France.
Merzouk A
No affiliation info available
Choquet D
No affiliation info available
Doutrellot PL
No affiliation info available
Ahmaidi S
No affiliation info available

MeSH

AnthropometryBlood PressureCoronary Artery DiseaseExerciseExercise TestHeart RateHumansIsometric ContractionMaleMiddle AgedMuscle, SkeletalOxygen ConsumptionPhysical EnduranceReference ValuesRest

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

12784167

Citation

Gayda, M, et al. "Aerobic Capacity and Peripheral Skeletal Muscle Function in Coronary Artery Disease Male Patients." International Journal of Sports Medicine, vol. 24, no. 4, 2003, pp. 258-63.
Gayda M, Merzouk A, Choquet D, et al. Aerobic capacity and peripheral skeletal muscle function in coronary artery disease male patients. Int J Sports Med. 2003;24(4):258-63.
Gayda, M., Merzouk, A., Choquet, D., Doutrellot, P. L., & Ahmaidi, S. (2003). Aerobic capacity and peripheral skeletal muscle function in coronary artery disease male patients. International Journal of Sports Medicine, 24(4), 258-63.
Gayda M, et al. Aerobic Capacity and Peripheral Skeletal Muscle Function in Coronary Artery Disease Male Patients. Int J Sports Med. 2003;24(4):258-63. PubMed PMID: 12784167.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Aerobic capacity and peripheral skeletal muscle function in coronary artery disease male patients. AU - Gayda,M, AU - Merzouk,A, AU - Choquet,D, AU - Doutrellot,P L, AU - Ahmaidi,S, PY - 2003/6/5/pubmed PY - 2003/10/3/medline PY - 2003/6/5/entrez SP - 258 EP - 63 JF - International journal of sports medicine JO - Int J Sports Med VL - 24 IS - 4 N2 - The aim of this study was to determine if the diminished aerobic capacity of coronary artery disease male (CAD) patients is accompanied by an impaired skeletal muscle function compared to healthy control subjects. Thirteen CAD patients and 9 healthy subjects performed both a maximal laboratory exercise testing and an assessment of the peripheral skeletal muscle function on an isokinetic apparatus. The cardiorespiratory and mechanical parameters were measured at ventilatory threshold and at maximal effort during a maximal exercise testing. The peripheral skeletal muscle function of the quadriceps was assessed from the maximal voluntary isometric force (MVIF) and from the static endurance time (SET) at an intensity of 50 % of the MVIF. The CAD patients showed a diminished aerobic capacity compared to healthy control subjects at maximal effort (maximal VO(2) uptake: p < 0.0001, maximal ventilation: p < 0.01; maximal heart rate: p < 0.0001, maximal power: p < 0.001) but also at VT (VO(2) uptake VT: p < 0.0001, Power VT: p < 0.001). No difference was found on the MVIF (p < 0.90) between the CAD patients and the control subjects whereas the SET was lower in the CAD patients (p < 0.01). The CAD patients had a lower aerobic capacity and an impaired skeletal muscle endurance compared to healthy subjects. SN - 0172-4622 UR - https://www.unboundmedicine.com/medline/citation/12784167/Aerobic_capacity_and_peripheral_skeletal_muscle_function_in_coronary_artery_disease_male_patients_ DB - PRIME DP - Unbound Medicine ER -