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Four new cycloartane glycosides from Aquilegia vulgaris and their immunosuppressive activities in mouse allogeneic mixed lymphocyte reaction.
Chem Pharm Bull (Tokyo). 2003 Jun; 51(6):683-7.CP

Abstract

Four new cycloartane glycosides, named aquilegiosides C-F, were isolated from the dried aerial parts of Aquilegia vulgaris. Their structures were determined by two dimensional (2D) NMR spectroscopic analysis and chemical evidence. Aquilegiosides C-F suppressed the proliferation of lymphocytes in mouse allogeneic mixed lymphocyte reaction with IC(50), ranging from 3.7x10(-5) to 2.2x10(-4) M.

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Authors+Show Affiliations

Nishida M
Faculty of Engineering, Kyushu Kyoritsu University, Kitakyushu, Japan.
Yoshimitsu H
No affiliation info available
Okawa M
No affiliation info available
Nohara T
No affiliation info available

MeSH

AnimalsAquilegiaCell DivisionGlycosidesImmunosuppressive AgentsIn Vitro TechniquesInhibitory Concentration 50LymphocytesMagnetic Resonance SpectroscopyMaleMiceMice, Inbred BALB CMice, Inbred C57BLMolecular StructurePlant Components, AerialPlant ExtractsTriterpenes

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12808247

Citation

Nishida, Makiko, et al. "Four New Cycloartane Glycosides From Aquilegia Vulgaris and Their Immunosuppressive Activities in Mouse Allogeneic Mixed Lymphocyte Reaction." Chemical & Pharmaceutical Bulletin, vol. 51, no. 6, 2003, pp. 683-7.
Nishida M, Yoshimitsu H, Okawa M, et al. Four new cycloartane glycosides from Aquilegia vulgaris and their immunosuppressive activities in mouse allogeneic mixed lymphocyte reaction. Chem Pharm Bull (Tokyo). 2003;51(6):683-7.
Nishida, M., Yoshimitsu, H., Okawa, M., & Nohara, T. (2003). Four new cycloartane glycosides from Aquilegia vulgaris and their immunosuppressive activities in mouse allogeneic mixed lymphocyte reaction. Chemical & Pharmaceutical Bulletin, 51(6), 683-7.
Nishida M, et al. Four New Cycloartane Glycosides From Aquilegia Vulgaris and Their Immunosuppressive Activities in Mouse Allogeneic Mixed Lymphocyte Reaction. Chem Pharm Bull (Tokyo). 2003;51(6):683-7. PubMed PMID: 12808247.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Four new cycloartane glycosides from Aquilegia vulgaris and their immunosuppressive activities in mouse allogeneic mixed lymphocyte reaction. AU - Nishida,Makiko, AU - Yoshimitsu,Hitoshi, AU - Okawa,Masafumi, AU - Nohara,Toshihiro, PY - 2003/6/17/pubmed PY - 2004/1/13/medline PY - 2003/6/17/entrez SP - 683 EP - 7 JF - Chemical & pharmaceutical bulletin JO - Chem Pharm Bull (Tokyo) VL - 51 IS - 6 N2 - Four new cycloartane glycosides, named aquilegiosides C-F, were isolated from the dried aerial parts of Aquilegia vulgaris. Their structures were determined by two dimensional (2D) NMR spectroscopic analysis and chemical evidence. Aquilegiosides C-F suppressed the proliferation of lymphocytes in mouse allogeneic mixed lymphocyte reaction with IC(50), ranging from 3.7x10(-5) to 2.2x10(-4) M. SN - 0009-2363 UR - https://www.unboundmedicine.com/medline/citation/12808247/Four_new_cycloartane_glycosides_from_Aquilegia_vulgaris_and_their_immunosuppressive_activities_in_mouse_allogeneic_mixed_lymphocyte_reaction_ L2 - https://joi.jlc.jst.go.jp/JST.JSTAGE/cpb/51.683?from=PubMed DB - PRIME DP - Unbound Medicine ER -