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Localized amyloidosis of seminal vesicle and vas deferens: report of two cases.
J Korean Med Sci. 2003 Jun; 18(3):447-51.JK

Abstract

We reported localized amyloidosis involving seminal vesicles and vasa deferentia, which was found in two patients with prostatic adenocarcinoma. A 60-yr-old (Case 1) and a 59-yr-old (Case 2) man came to our hospital with elevation of serum prostate-specific antigen (PSA) and biopsy proven carcinoma, respectively. MRI revealed multiple irregular foci of low signal intensity in the prostates as well as in both seminal vesicles and vasa deferentia on T2-weighted imaging, suggesting prostatic carcinoma with extension to both seminal vesicles and vasa deferentia in both cases. Under the clinical diagnosis of stage III prostatic adenocarcinoma, a radical prostatectomy was performed in both patients. Microscopically, Gleason score 7 adenocarcinoma was observed in both patients. In addition, isolated amyloidosis of both seminal vesicles and vasa deferentia was found without carcinoma involvement. Localized amyloidosis in the seminal vesicles, which is considered as senile process, has been occasionally reported in the autopsy and in the surgical specimens. Amyloid deposition in the vas deferens has also been reported in the literature, however, the deposition mimicking extension of carcinoma has not been reported. In this report, two cases of isolated amyloidosis of the seminal vesicles and vasa deferentia are described with electron microscopic study and literature review.

Links

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Authors+Show Affiliations

Jun SY
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Kim KR
No affiliation info available
Cho KS
No affiliation info available
Ro JY
No affiliation info available

MeSH

AdenocarcinomaAmyloidosisHumansMaleMiddle AgedProstatic NeoplasmsSeminal VesiclesVas Deferens

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

12808339

Citation

Jun, Sun-Young, et al. "Localized Amyloidosis of Seminal Vesicle and Vas Deferens: Report of Two Cases." Journal of Korean Medical Science, vol. 18, no. 3, 2003, pp. 447-51.
Jun SY, Kim KR, Cho KS, et al. Localized amyloidosis of seminal vesicle and vas deferens: report of two cases. J Korean Med Sci. 2003;18(3):447-51.
Jun, S. Y., Kim, K. R., Cho, K. S., & Ro, J. Y. (2003). Localized amyloidosis of seminal vesicle and vas deferens: report of two cases. Journal of Korean Medical Science, 18(3), 447-51.
Jun SY, et al. Localized Amyloidosis of Seminal Vesicle and Vas Deferens: Report of Two Cases. J Korean Med Sci. 2003;18(3):447-51. PubMed PMID: 12808339.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Localized amyloidosis of seminal vesicle and vas deferens: report of two cases. AU - Jun,Sun-Young, AU - Kim,Kyu-Rae, AU - Cho,Kyoung-Sik, AU - Ro,Jae Y, PY - 2003/6/17/pubmed PY - 2004/2/24/medline PY - 2003/6/17/entrez SP - 447 EP - 51 JF - Journal of Korean medical science JO - J Korean Med Sci VL - 18 IS - 3 N2 - We reported localized amyloidosis involving seminal vesicles and vasa deferentia, which was found in two patients with prostatic adenocarcinoma. A 60-yr-old (Case 1) and a 59-yr-old (Case 2) man came to our hospital with elevation of serum prostate-specific antigen (PSA) and biopsy proven carcinoma, respectively. MRI revealed multiple irregular foci of low signal intensity in the prostates as well as in both seminal vesicles and vasa deferentia on T2-weighted imaging, suggesting prostatic carcinoma with extension to both seminal vesicles and vasa deferentia in both cases. Under the clinical diagnosis of stage III prostatic adenocarcinoma, a radical prostatectomy was performed in both patients. Microscopically, Gleason score 7 adenocarcinoma was observed in both patients. In addition, isolated amyloidosis of both seminal vesicles and vasa deferentia was found without carcinoma involvement. Localized amyloidosis in the seminal vesicles, which is considered as senile process, has been occasionally reported in the autopsy and in the surgical specimens. Amyloid deposition in the vas deferens has also been reported in the literature, however, the deposition mimicking extension of carcinoma has not been reported. In this report, two cases of isolated amyloidosis of the seminal vesicles and vasa deferentia are described with electron microscopic study and literature review. SN - 1011-8934 UR - https://www.unboundmedicine.com/medline/citation/12808339/Localized_amyloidosis_of_seminal_vesicle_and_vas_deferens:_report_of_two_cases_ DB - PRIME DP - Unbound Medicine ER -