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[The anaylsis of mortality rate according to CTP score and MELD score in patients with liver cirrhosis].
Taehan Kan Hakhoe Chi. 2003 Jun; 9(2):98-106.TK

Abstract

BACKGROUND/AIMS

The Model for End-Stage Liver Disease (MELD) consists of serum bilirubin and creatinine levels, International Normalized Ratio (INR) for prothrombin time, and etiology of liver disease. The MELD score is a reliable measurement of mortality risk and is suitable for a disease severity index in patients with end-stage liver disease. We examined the validity of the MELD as a disease severity index for patients with end-stage liver disease.

METHODS

We investigated the 379 patients with liver cirrhosis hospitalized between January 1995 and May 2001. We retrospectively reviewed the hospital records to verify the diagnosis of cirrhosis and to collect exact patient information about their demographic data, portal hypertensive complications and laboratory data. The ability to classify patients with liver cirrhosis according to their risk of death was examined using the concordance c-statistic.

RESULTS

The MELD score performed well in predicting death within 3 months with a c-statistic of 0.73 with etiology and 0.71 without etiology. The significant clinical, laboratory variables on 3 month survival in patients with liver cirrhosis are serum bilirubin, ascites and hepatic encephalopathy. The addition of portal hypertensive complications to the MELD score did not improve the accuracy of the MELD score.

CONCLUSIONS

The MELD score is a useful disease severity index for the patients with end-stage liver disease and provides reliable measurement of short term survival over a wide range of liver disease severity and diverse etiology.

Authors+Show Affiliations

Department of Internal Medicine, Pochon CHA University College of Medicine, Sungnam, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

kor

PubMed ID

12824749

Citation

Jeong, Eun Mi, et al. "[The Anaylsis of Mortality Rate According to CTP Score and MELD Score in Patients With Liver Cirrhosis]." Taehan Kan Hakhoe Chi = the Korean Journal of Hepatology, vol. 9, no. 2, 2003, pp. 98-106.
Jeong EM, Hwang SG, Park HH, et al. [The anaylsis of mortality rate according to CTP score and MELD score in patients with liver cirrhosis]. Taehan Kan Hakhoe Chi. 2003;9(2):98-106.
Jeong, E. M., Hwang, S. G., Park, H. H., Park, J. H., Kim, H. T., Oh, S. W., Kho, K. H., Hong, S. P., Park, P. W., Rim, G. S., & Kim, S. H. (2003). [The anaylsis of mortality rate according to CTP score and MELD score in patients with liver cirrhosis]. Taehan Kan Hakhoe Chi = the Korean Journal of Hepatology, 9(2), 98-106.
Jeong EM, et al. [The Anaylsis of Mortality Rate According to CTP Score and MELD Score in Patients With Liver Cirrhosis]. Taehan Kan Hakhoe Chi. 2003;9(2):98-106. PubMed PMID: 12824749.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The anaylsis of mortality rate according to CTP score and MELD score in patients with liver cirrhosis]. AU - Jeong,Eun Mi, AU - Hwang,Seong Gyu, AU - Park,Hong Hoon, AU - Park,Ji Han, AU - Kim,Hyung Tae, AU - Oh,Seong Wook, AU - Kho,Kwang Hyun, AU - Hong,Sung Pyo, AU - Park,Phil Won, AU - Rim,Gyu Sung, AU - Kim,Se Hyun, PY - 2003/6/26/pubmed PY - 2004/4/16/medline PY - 2003/6/26/entrez SP - 98 EP - 106 JF - Taehan Kan Hakhoe chi = The Korean journal of hepatology JO - Taehan Kan Hakhoe Chi VL - 9 IS - 2 N2 - BACKGROUND/AIMS: The Model for End-Stage Liver Disease (MELD) consists of serum bilirubin and creatinine levels, International Normalized Ratio (INR) for prothrombin time, and etiology of liver disease. The MELD score is a reliable measurement of mortality risk and is suitable for a disease severity index in patients with end-stage liver disease. We examined the validity of the MELD as a disease severity index for patients with end-stage liver disease. METHODS: We investigated the 379 patients with liver cirrhosis hospitalized between January 1995 and May 2001. We retrospectively reviewed the hospital records to verify the diagnosis of cirrhosis and to collect exact patient information about their demographic data, portal hypertensive complications and laboratory data. The ability to classify patients with liver cirrhosis according to their risk of death was examined using the concordance c-statistic. RESULTS: The MELD score performed well in predicting death within 3 months with a c-statistic of 0.73 with etiology and 0.71 without etiology. The significant clinical, laboratory variables on 3 month survival in patients with liver cirrhosis are serum bilirubin, ascites and hepatic encephalopathy. The addition of portal hypertensive complications to the MELD score did not improve the accuracy of the MELD score. CONCLUSIONS: The MELD score is a useful disease severity index for the patients with end-stage liver disease and provides reliable measurement of short term survival over a wide range of liver disease severity and diverse etiology. SN - 1226-0479 UR - https://www.unboundmedicine.com/medline/citation/12824749/[The_anaylsis_of_mortality_rate_according_to_CTP_score_and_MELD_score_in_patients_with_liver_cirrhosis]_ L2 - https://medlineplus.gov/cirrhosis.html DB - PRIME DP - Unbound Medicine ER -