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Management of food allergies.

Abstract

Worldwide, approximately 8 and 2% of children and adults, respectively, suffer from food allergy. Cow's milk, egg, peanut, soy, wheat, fish, shellfish and tree nuts are responsible for the majority of allergic reactions to foods. Allergic reactions to food can occur by a variety of immune mechanisms including: IgE-mediated; non-IgE-mediated (T-cell-mediated); and combined IgE- and T-cell-mediated. Food allergies can affect any organ system, but most frequently involve the gastrointestinal system, the skin and the respiratory system. Knowledge of the spectrum of food allergies is important in order to identify patients at risk for severe or life-threatening allergic reactions. This article will review the mechanisms of specific food allergy disorders. It will also summarise the diagnosis of food allergy including the history of a food reaction, skin tests and laboratory tests. The management of food allergy will also be discussed with particular emphasis on the avoidance of food allergens and the pharmacotherapy of allergic reactions. Future therapy for food allergies will also be discussed.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Division of Allergy and Immunology, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 34th Street and Civic Center Blvd, Philadelphia, PA 19104, USA. Fogg@email.chop.edu

    Source

    Expert opinion on pharmacotherapy 4:7 2003 Jul pg 1025-37

    MeSH

    Adolescent
    Adult
    Anaphylaxis
    Child
    Dermatitis, Atopic
    Female
    Food Hypersensitivity
    Histamine H1 Antagonists
    Humans
    Male
    Prevalence
    Risk Factors
    Skin Tests

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    12831331

    Citation

    Fogg, Matthew I., and Jonathan M. Spergel. "Management of Food Allergies." Expert Opinion On Pharmacotherapy, vol. 4, no. 7, 2003, pp. 1025-37.
    Fogg MI, Spergel JM. Management of food allergies. Expert Opin Pharmacother. 2003;4(7):1025-37.
    Fogg, M. I., & Spergel, J. M. (2003). Management of food allergies. Expert Opinion On Pharmacotherapy, 4(7), pp. 1025-37.
    Fogg MI, Spergel JM. Management of Food Allergies. Expert Opin Pharmacother. 2003;4(7):1025-37. PubMed PMID: 12831331.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Management of food allergies. AU - Fogg,Matthew I, AU - Spergel,Jonathan M, PY - 2003/7/2/pubmed PY - 2003/8/20/medline PY - 2003/7/2/entrez SP - 1025 EP - 37 JF - Expert opinion on pharmacotherapy JO - Expert Opin Pharmacother VL - 4 IS - 7 N2 - Worldwide, approximately 8 and 2% of children and adults, respectively, suffer from food allergy. Cow's milk, egg, peanut, soy, wheat, fish, shellfish and tree nuts are responsible for the majority of allergic reactions to foods. Allergic reactions to food can occur by a variety of immune mechanisms including: IgE-mediated; non-IgE-mediated (T-cell-mediated); and combined IgE- and T-cell-mediated. Food allergies can affect any organ system, but most frequently involve the gastrointestinal system, the skin and the respiratory system. Knowledge of the spectrum of food allergies is important in order to identify patients at risk for severe or life-threatening allergic reactions. This article will review the mechanisms of specific food allergy disorders. It will also summarise the diagnosis of food allergy including the history of a food reaction, skin tests and laboratory tests. The management of food allergy will also be discussed with particular emphasis on the avoidance of food allergens and the pharmacotherapy of allergic reactions. Future therapy for food allergies will also be discussed. SN - 1465-6566 UR - https://www.unboundmedicine.com/medline/citation/12831331/Management_of_food_allergies_ L2 - http://www.tandfonline.com/doi/full/10.1517/14656566.4.7.1025 DB - PRIME DP - Unbound Medicine ER -