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Citalopram treatment of children and adolescents with obsessive-compulsive disorder: a preliminary report.
Psychiatry Clin Neurosci. 2003 Aug; 57(4):405-8.PC

Abstract

The purpose of the present study was to assess the efficacy and tolerability of citalopram in the acute treatment of children and adolescents with obsessive compulsive disorder (OCD) during an 8-week, open-label study. Fifteen patients (six female, nine male) with a mean age of 12.1 +/- 3.3 years (range: 6-17 years) were treated with citalopram (range of dose: 20-30 mg/day, mean dose: 24 +/- 5.5 mg/day). The children's version of the Yale-Brown Obsessive-Compulsive scale (CY-BOCS) was rated at the baseline, at the 4th week and at the 8th week of treatment. Fourteen patients had a decrease in total score of CY-BOCS from baseline to the 4th week of treatment (P < 0.01) and the 8th week of treatment (P < 0.01). Sedation (n = 1) and insomnia (n = 1) were reported in the first weeks of treatment. The primary data suggest the efficacy and tolerability of citalopram in young patients with OCD.

Authors+Show Affiliations

Department of Child and Adolescent Psychiatry, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. nmotavalli@yahoo.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

12839522

Citation

Mukaddes, Nahit Motavallý, et al. "Citalopram Treatment of Children and Adolescents With Obsessive-compulsive Disorder: a Preliminary Report." Psychiatry and Clinical Neurosciences, vol. 57, no. 4, 2003, pp. 405-8.
Mukaddes NM, Abali O, Kaynak N. Citalopram treatment of children and adolescents with obsessive-compulsive disorder: a preliminary report. Psychiatry Clin Neurosci. 2003;57(4):405-8.
Mukaddes, N. M., Abali, O., & Kaynak, N. (2003). Citalopram treatment of children and adolescents with obsessive-compulsive disorder: a preliminary report. Psychiatry and Clinical Neurosciences, 57(4), 405-8.
Mukaddes NM, Abali O, Kaynak N. Citalopram Treatment of Children and Adolescents With Obsessive-compulsive Disorder: a Preliminary Report. Psychiatry Clin Neurosci. 2003;57(4):405-8. PubMed PMID: 12839522.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Citalopram treatment of children and adolescents with obsessive-compulsive disorder: a preliminary report. AU - Mukaddes,Nahit Motavallý, AU - Abali,Osman, AU - Kaynak,Nimet, PY - 2003/7/4/pubmed PY - 2003/9/10/medline PY - 2003/7/4/entrez SP - 405 EP - 8 JF - Psychiatry and clinical neurosciences JO - Psychiatry Clin Neurosci VL - 57 IS - 4 N2 - The purpose of the present study was to assess the efficacy and tolerability of citalopram in the acute treatment of children and adolescents with obsessive compulsive disorder (OCD) during an 8-week, open-label study. Fifteen patients (six female, nine male) with a mean age of 12.1 +/- 3.3 years (range: 6-17 years) were treated with citalopram (range of dose: 20-30 mg/day, mean dose: 24 +/- 5.5 mg/day). The children's version of the Yale-Brown Obsessive-Compulsive scale (CY-BOCS) was rated at the baseline, at the 4th week and at the 8th week of treatment. Fourteen patients had a decrease in total score of CY-BOCS from baseline to the 4th week of treatment (P < 0.01) and the 8th week of treatment (P < 0.01). Sedation (n = 1) and insomnia (n = 1) were reported in the first weeks of treatment. The primary data suggest the efficacy and tolerability of citalopram in young patients with OCD. SN - 1323-1316 UR - https://www.unboundmedicine.com/medline/citation/12839522/Citalopram_treatment_of_children_and_adolescents_with_obsessive_compulsive_disorder:_a_preliminary_report_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&amp;sid=nlm:pubmed&amp;issn=1323-1316&amp;date=2003&amp;volume=57&amp;issue=4&amp;spage=405 DB - PRIME DP - Unbound Medicine ER -