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Chlamydia pneumoniae in children with MS: frequency and quantity of intrathecal antibodies.
Neurology 2003; 61(1):125-8Neur

Abstract

The authors investigated the frequency and quantity of intrathecal antibody synthesis against Chlamydia pneumoniae and the presence of C pneumoniae antigen in 25 children with MS. C pneumoniae genome was present in two children. In seven children an intrathecal synthesis of C pneumoniae antibodies was detected, representing only a small part of the total intrathecal immunoglobulin G, suggesting that this intrathecal synthesis is part of a polyspecific, oligoclonal immune response.

Authors+Show Affiliations

Department of Pediatric Neurology, University of Göttingen, Germany. Krostasy@excite.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12847174

Citation

Rostasy, K, et al. "Chlamydia Pneumoniae in Children With MS: Frequency and Quantity of Intrathecal Antibodies." Neurology, vol. 61, no. 1, 2003, pp. 125-8.
Rostasy K, Reiber H, Pohl D, et al. Chlamydia pneumoniae in children with MS: frequency and quantity of intrathecal antibodies. Neurology. 2003;61(1):125-8.
Rostasy, K., Reiber, H., Pohl, D., Lange, P., Ohlenbusch, A., Eiffert, H., ... Hanefeld, F. (2003). Chlamydia pneumoniae in children with MS: frequency and quantity of intrathecal antibodies. Neurology, 61(1), pp. 125-8.
Rostasy K, et al. Chlamydia Pneumoniae in Children With MS: Frequency and Quantity of Intrathecal Antibodies. Neurology. 2003 Jul 8;61(1):125-8. PubMed PMID: 12847174.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chlamydia pneumoniae in children with MS: frequency and quantity of intrathecal antibodies. AU - Rostasy,K, AU - Reiber,H, AU - Pohl,D, AU - Lange,P, AU - Ohlenbusch,A, AU - Eiffert,H, AU - Maass,M, AU - Hanefeld,F, PY - 2003/7/9/pubmed PY - 2004/1/30/medline PY - 2003/7/9/entrez SP - 125 EP - 8 JF - Neurology JO - Neurology VL - 61 IS - 1 N2 - The authors investigated the frequency and quantity of intrathecal antibody synthesis against Chlamydia pneumoniae and the presence of C pneumoniae antigen in 25 children with MS. C pneumoniae genome was present in two children. In seven children an intrathecal synthesis of C pneumoniae antibodies was detected, representing only a small part of the total intrathecal immunoglobulin G, suggesting that this intrathecal synthesis is part of a polyspecific, oligoclonal immune response. SN - 1526-632X UR - https://www.unboundmedicine.com/medline/citation/12847174/Chlamydia_pneumoniae_in_children_with_MS:_frequency_and_quantity_of_intrathecal_antibodies_ L2 - http://www.neurology.org/cgi/pmidlookup?view=long&pmid=12847174 DB - PRIME DP - Unbound Medicine ER -