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The co-expression of VR1 and VRL-1 in the rat vagal sensory ganglia.
Brain Res. 2003 Aug 08; 980(2):293-6.BR

Abstract

Immunohistochemistry for two nociceptive transducers, the vanilloid receptor 1 (VR1) and vanilloid receptor 1-like receptor (VRL-1), was performed on the vagal sensory ganglia. In the jugular ganglion, VR1-immunoreactive (IR) neurons were small to medium-sized (range 49.7-1,125.6 microm(2), mean+/-S.D. 407.7+/-219.7 microm(2)), whereas VRL-1-IR neurons were medium-sized to large (range 223.6-1,341.1 microm(2), mean+/-S.D. 584.3+/-253.5 microm(2)). In the nodose ganglion, VR1- and VRL-1-IR neurons were mostly small to medium-sized (VR1: range 148.5-1464.4 microm(2), mean+/-S.D. 554.3+/-207.4 microm(2); VRL-1: range 161.7-1166.2 microm(2), mean+/-S.D. 541.9+/-186.2 microm(2)). The double immunofluorescence method revealed that co-expression of VR1-immunoreactivity among VRL-1-IR neurons was more abundant in the nodose ganglion (63%) than in the jugular ganglion (4%). The present study suggests that co-expression of VR1 and VRL-1 may be more common in visceral sensory neurons than in somatic sensory neurons.

Authors+Show Affiliations

Department of Oral Function and Anatomy, and Biodental Research Center, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama 700-8525, Japan. hiroichi@md.okayama-u.ac.jpNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12867271

Citation

Ichikawa, H, and T Sugimoto. "The Co-expression of VR1 and VRL-1 in the Rat Vagal Sensory Ganglia." Brain Research, vol. 980, no. 2, 2003, pp. 293-6.
Ichikawa H, Sugimoto T. The co-expression of VR1 and VRL-1 in the rat vagal sensory ganglia. Brain Res. 2003;980(2):293-6.
Ichikawa, H., & Sugimoto, T. (2003). The co-expression of VR1 and VRL-1 in the rat vagal sensory ganglia. Brain Research, 980(2), 293-6.
Ichikawa H, Sugimoto T. The Co-expression of VR1 and VRL-1 in the Rat Vagal Sensory Ganglia. Brain Res. 2003 Aug 8;980(2):293-6. PubMed PMID: 12867271.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The co-expression of VR1 and VRL-1 in the rat vagal sensory ganglia. AU - Ichikawa,H, AU - Sugimoto,T, PY - 2003/7/18/pubmed PY - 2003/9/17/medline PY - 2003/7/18/entrez SP - 293 EP - 6 JF - Brain research JO - Brain Res. VL - 980 IS - 2 N2 - Immunohistochemistry for two nociceptive transducers, the vanilloid receptor 1 (VR1) and vanilloid receptor 1-like receptor (VRL-1), was performed on the vagal sensory ganglia. In the jugular ganglion, VR1-immunoreactive (IR) neurons were small to medium-sized (range 49.7-1,125.6 microm(2), mean+/-S.D. 407.7+/-219.7 microm(2)), whereas VRL-1-IR neurons were medium-sized to large (range 223.6-1,341.1 microm(2), mean+/-S.D. 584.3+/-253.5 microm(2)). In the nodose ganglion, VR1- and VRL-1-IR neurons were mostly small to medium-sized (VR1: range 148.5-1464.4 microm(2), mean+/-S.D. 554.3+/-207.4 microm(2); VRL-1: range 161.7-1166.2 microm(2), mean+/-S.D. 541.9+/-186.2 microm(2)). The double immunofluorescence method revealed that co-expression of VR1-immunoreactivity among VRL-1-IR neurons was more abundant in the nodose ganglion (63%) than in the jugular ganglion (4%). The present study suggests that co-expression of VR1 and VRL-1 may be more common in visceral sensory neurons than in somatic sensory neurons. SN - 0006-8993 UR - https://www.unboundmedicine.com/medline/citation/12867271/The_co_expression_of_VR1_and_VRL_1_in_the_rat_vagal_sensory_ganglia_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0006899303029986 DB - PRIME DP - Unbound Medicine ER -