Rh(I)-catalyzed direct ortho-alkenylation of aromatic ketimines with alkynes and its application to the synthesis of isoquinoline derivatives.Org Lett. 2003 Jul 24; 5(15):2759-61.OL
Abstract
[reaction: see text] Novel synthetic methods of both ortho-alkenylated aromatic ketones and isoquinoline derivatives have been developed through the Rh(I)-catalyzed direct ortho-alkenylation of common aromatic ketimines with alkynes. Furthermore, a highly efficient one-pot synthesis of isoquinoline derivatives was achieved by simply mixing aromatic ketone, benzylamine, and alkyne under a Rh(I) catalyst.
Pub Type(s)
Journal Article
Language
eng
PubMed ID
12868908
Citation
Lim, Sung-Gon, et al. "Rh(I)-catalyzed Direct Ortho-alkenylation of Aromatic Ketimines With Alkynes and Its Application to the Synthesis of Isoquinoline Derivatives." Organic Letters, vol. 5, no. 15, 2003, pp. 2759-61.
Lim SG, Lee JH, Moon CW, et al. Rh(I)-catalyzed direct ortho-alkenylation of aromatic ketimines with alkynes and its application to the synthesis of isoquinoline derivatives. Org Lett. 2003;5(15):2759-61.
Lim, S. G., Lee, J. H., Moon, C. W., Hong, J. B., & Jun, C. H. (2003). Rh(I)-catalyzed direct ortho-alkenylation of aromatic ketimines with alkynes and its application to the synthesis of isoquinoline derivatives. Organic Letters, 5(15), 2759-61.
Lim SG, et al. Rh(I)-catalyzed Direct Ortho-alkenylation of Aromatic Ketimines With Alkynes and Its Application to the Synthesis of Isoquinoline Derivatives. Org Lett. 2003 Jul 24;5(15):2759-61. PubMed PMID: 12868908.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Rh(I)-catalyzed direct ortho-alkenylation of aromatic ketimines with alkynes and its application to the synthesis of isoquinoline derivatives.
AU - Lim,Sung-Gon,
AU - Lee,Jun Hee,
AU - Moon,Choong Woon,
AU - Hong,Jun-Bae,
AU - Jun,Chul-Ho,
PY - 2003/7/19/pubmed
PY - 2003/7/19/medline
PY - 2003/7/19/entrez
SP - 2759
EP - 61
JF - Organic letters
JO - Org Lett
VL - 5
IS - 15
N2 - [reaction: see text] Novel synthetic methods of both ortho-alkenylated aromatic ketones and isoquinoline derivatives have been developed through the Rh(I)-catalyzed direct ortho-alkenylation of common aromatic ketimines with alkynes. Furthermore, a highly efficient one-pot synthesis of isoquinoline derivatives was achieved by simply mixing aromatic ketone, benzylamine, and alkyne under a Rh(I) catalyst.
SN - 1523-7060
UR - https://www.unboundmedicine.com/medline/citation/12868908/Rh_I__catalyzed_direct_ortho_alkenylation_of_aromatic_ketimines_with_alkynes_and_its_application_to_the_synthesis_of_isoquinoline_derivatives_
DB - PRIME
DP - Unbound Medicine
ER -
