Tags

Type your tag names separated by a space and hit enter

[Correlation between CA-125 marker with the presence and severity of pelvic endometriosis].
Rev Med Chil. 2003 Apr; 131(4):367-72.RM

Abstract

BACKGROUND

Endometriosis affects at least 15% of infertile women. The diagnosis is made by direct visualization of implants either at laparoscopy or laparotomy. Elevation of plasma CA-125 levels has been associated with the presence of endometriosis.

AIM

To search for a correlation between CA-125 and the presence of endometriosis and its severity, among infertile patients requesting a diagnostic laparoscopy.

PATIENTS AND METHODS

A total of 117 women were prospectively enrolled in the study between May 2000 and March 2002. A serum sample for CA-125 was taken immediately before surgery and the value obtained was correlated with the presence or absence of endometriosis and the severity of the disease.

RESULTS

Sixty nine patients had endometriosis (59%). Patients with severe endometriosis, or grade IV, showed statistically significant higher levels of CA-125 compared to women without endometriosis or with grades I, II or III of the disease.

DISCUSSION

The overall sensibility of CA-125 in detecting patients with endometriosis was low, however, it worked better for patients with advanced disease. Considering the rather low cost and simplicity of the test, we believe that it should be included in the evaluation of infertile couples.

Authors+Show Affiliations

Unidad de Reproducción Humana, Departamento de Obstetricia y Ginecología, Facultad de Medicina, Pontificia Universidad Católica de Chile. mbianchi@med.puc.clNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

spa

PubMed ID

12870230

Citation

Bianchi, Marcelo, et al. "[Correlation Between CA-125 Marker With the Presence and Severity of Pelvic Endometriosis]." Revista Medica De Chile, vol. 131, no. 4, 2003, pp. 367-72.
Bianchi M, Macaya R, Durruty G, et al. [Correlation between CA-125 marker with the presence and severity of pelvic endometriosis]. Rev Med Chil. 2003;131(4):367-72.
Bianchi, M., Macaya, R., Durruty, G., & Manzur, A. (2003). [Correlation between CA-125 marker with the presence and severity of pelvic endometriosis]. Revista Medica De Chile, 131(4), 367-72.
Bianchi M, et al. [Correlation Between CA-125 Marker With the Presence and Severity of Pelvic Endometriosis]. Rev Med Chil. 2003;131(4):367-72. PubMed PMID: 12870230.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Correlation between CA-125 marker with the presence and severity of pelvic endometriosis]. AU - Bianchi,Marcelo, AU - Macaya,Rodrigo, AU - Durruty,Guillermo, AU - Manzur,Alejandro, PY - 2003/7/23/pubmed PY - 2003/9/13/medline PY - 2003/7/23/entrez SP - 367 EP - 72 JF - Revista medica de Chile JO - Rev Med Chil VL - 131 IS - 4 N2 - BACKGROUND: Endometriosis affects at least 15% of infertile women. The diagnosis is made by direct visualization of implants either at laparoscopy or laparotomy. Elevation of plasma CA-125 levels has been associated with the presence of endometriosis. AIM: To search for a correlation between CA-125 and the presence of endometriosis and its severity, among infertile patients requesting a diagnostic laparoscopy. PATIENTS AND METHODS: A total of 117 women were prospectively enrolled in the study between May 2000 and March 2002. A serum sample for CA-125 was taken immediately before surgery and the value obtained was correlated with the presence or absence of endometriosis and the severity of the disease. RESULTS: Sixty nine patients had endometriosis (59%). Patients with severe endometriosis, or grade IV, showed statistically significant higher levels of CA-125 compared to women without endometriosis or with grades I, II or III of the disease. DISCUSSION: The overall sensibility of CA-125 in detecting patients with endometriosis was low, however, it worked better for patients with advanced disease. Considering the rather low cost and simplicity of the test, we believe that it should be included in the evaluation of infertile couples. SN - 0034-9887 UR - https://www.unboundmedicine.com/medline/citation/12870230/[Correlation_between_CA_125_marker_with_the_presence_and_severity_of_pelvic_endometriosis]_ L2 - http://www.diseaseinfosearch.org/result/2537 DB - PRIME DP - Unbound Medicine ER -