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Regional differences in HIV trends in The Gambia: results from sentinel surveillance among pregnant women.
AIDS. 2003 Aug 15; 17(12):1841-6.AIDS

Abstract

OBJECTIVE

To monitor HIV-1 and HIV-2 trends in The Gambia, West Africa.

METHODS

In 1993-1995 a nationwide survey among 29 670 pregnant women attending eight antenatal clinics estimated the seroprevalence of HIV-1 at 0.6%, and of HIV-2 at 1.1%. Five years later, sentinel surveillance in pregnant women was established, using unlinked anonymous testing in four clinics. A dried blood spot on filter paper was obtained and tested for HIV antibodies.

RESULTS

Between May 2000 and August 2001, 8054 analysable samples were collected at four sites. The prevalence of HIV-1 rose sharply in one rural area from 0.6 to 3.0% (P < 0.0001), but the increase was small and non-significant in two other rural sites and in the urban site. The prevalence of HIV-2 did not change significantly at any of the sites. The overall prevalence of HIV-1 was 1.0% [95% confidence interval (CI) 0.8-1.3%], and of HIV-2 0.8% (CI 0.6-1.0%). Site, nationality and higher age were significantly associated with HIV-1 infection, and higher parity and site were significantly associated with HIV-2 infection.

CONCLUSION

Fifteen years after the first case of HIV-1 was described in The Gambia, the epidemic is still at a low level. There is heterogeneity within the country, with one rural area experiencing a fivefold increase in 6 years. The prevalence of HIV-2 in The Gambia is stable.

Authors+Show Affiliations

Medical Research Council Laboratories, The Gambia. maartin.schim@lshtm.ac.ukNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12891071

Citation

Schim van der Loeff, Maarten F., et al. "Regional Differences in HIV Trends in the Gambia: Results From Sentinel Surveillance Among Pregnant Women." AIDS (London, England), vol. 17, no. 12, 2003, pp. 1841-6.
Schim van der Loeff MF, Sarge-Njie R, Ceesay S, et al. Regional differences in HIV trends in The Gambia: results from sentinel surveillance among pregnant women. AIDS. 2003;17(12):1841-6.
Schim van der Loeff, M. F., Sarge-Njie, R., Ceesay, S., Awasana, A. A., Jaye, P., Sam, O., Jaiteh, K. O., Cubitt, D., Milligan, P., & Whittle, H. C. (2003). Regional differences in HIV trends in The Gambia: results from sentinel surveillance among pregnant women. AIDS (London, England), 17(12), 1841-6.
Schim van der Loeff MF, et al. Regional Differences in HIV Trends in the Gambia: Results From Sentinel Surveillance Among Pregnant Women. AIDS. 2003 Aug 15;17(12):1841-6. PubMed PMID: 12891071.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Regional differences in HIV trends in The Gambia: results from sentinel surveillance among pregnant women. AU - Schim van der Loeff,Maarten F, AU - Sarge-Njie,Ramu, AU - Ceesay,Saihou, AU - Awasana,Akum Aveika, AU - Jaye,Pa, AU - Sam,Omar, AU - Jaiteh,Kebba O, AU - Cubitt,David, AU - Milligan,Paul, AU - Whittle,Hilton C, PY - 2003/8/2/pubmed PY - 2003/10/8/medline PY - 2003/8/2/entrez SP - 1841 EP - 6 JF - AIDS (London, England) JO - AIDS VL - 17 IS - 12 N2 - OBJECTIVE: To monitor HIV-1 and HIV-2 trends in The Gambia, West Africa. METHODS: In 1993-1995 a nationwide survey among 29 670 pregnant women attending eight antenatal clinics estimated the seroprevalence of HIV-1 at 0.6%, and of HIV-2 at 1.1%. Five years later, sentinel surveillance in pregnant women was established, using unlinked anonymous testing in four clinics. A dried blood spot on filter paper was obtained and tested for HIV antibodies. RESULTS: Between May 2000 and August 2001, 8054 analysable samples were collected at four sites. The prevalence of HIV-1 rose sharply in one rural area from 0.6 to 3.0% (P < 0.0001), but the increase was small and non-significant in two other rural sites and in the urban site. The prevalence of HIV-2 did not change significantly at any of the sites. The overall prevalence of HIV-1 was 1.0% [95% confidence interval (CI) 0.8-1.3%], and of HIV-2 0.8% (CI 0.6-1.0%). Site, nationality and higher age were significantly associated with HIV-1 infection, and higher parity and site were significantly associated with HIV-2 infection. CONCLUSION: Fifteen years after the first case of HIV-1 was described in The Gambia, the epidemic is still at a low level. There is heterogeneity within the country, with one rural area experiencing a fivefold increase in 6 years. The prevalence of HIV-2 in The Gambia is stable. SN - 0269-9370 UR - https://www.unboundmedicine.com/medline/citation/12891071/Regional_differences_in_HIV_trends_in_The_Gambia:_results_from_sentinel_surveillance_among_pregnant_women_ L2 - https://doi.org/10.1097/01.aids.0000076303.76477.49 DB - PRIME DP - Unbound Medicine ER -