Tags

Type your tag names separated by a space and hit enter

Alcohol consumption and the incidence of Parkinson's disease.
Ann Neurol. 2003 Aug; 54(2):170-5.AN

Abstract

Cigarette smoking and caffeine consumption are associated with a decreased incidence of Parkinson's disease (PD). This inverse association may result from neuroprotective effects of cigarette smoke and caffeine, or from a disinclination of future PD patients to engage in habituating behaviors. We investigated the association between consumption of alcoholic beverages, another potentially habituating behavior, and risk of PD in two large prospective cohorts Nurses' Health Study, and Health Professionals' Follow-up Study. We detected 415 new cases of PD during follow-up. Compared with nondrinkers at baseline, the relative rate (95% confidence interval) was 1.0 (0.8-1.3) for drinkers of less than 5 gm/day, 1.0 (0.8-1.4) for 5 to less than 15 gm/day, 1.1 (0.8-1.6) for 15 to less than 30 gm/day, and 0.7 (0.5-1.2) for 30 gm/day or more (p for trend = 0.45). Consumption of wine or liquor was not associated with the incidence of PD. Compared with those who consumed beer less than once per month, the relative rate (95% confidence interval) was 0.7 (0.5-0.9) for one to three drinks of beer per month, and 0.7 (0.5, 0.9) for one or more drinks of beer per week. The risk of PD was similar in individuals who usually consume moderate amounts of alcohol and in abstainers.

Authors+Show Affiliations

Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA. miguel_hernan@post.harvard.eduNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

12891669

Citation

Hernán, Miguel A., et al. "Alcohol Consumption and the Incidence of Parkinson's Disease." Annals of Neurology, vol. 54, no. 2, 2003, pp. 170-5.
Hernán MA, Chen H, Schwarzschild MA, et al. Alcohol consumption and the incidence of Parkinson's disease. Ann Neurol. 2003;54(2):170-5.
Hernán, M. A., Chen, H., Schwarzschild, M. A., & Ascherio, A. (2003). Alcohol consumption and the incidence of Parkinson's disease. Annals of Neurology, 54(2), 170-5.
Hernán MA, et al. Alcohol Consumption and the Incidence of Parkinson's Disease. Ann Neurol. 2003;54(2):170-5. PubMed PMID: 12891669.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcohol consumption and the incidence of Parkinson's disease. AU - Hernán,Miguel A, AU - Chen,Honglei, AU - Schwarzschild,Michael A, AU - Ascherio,Alberto, PY - 2003/8/2/pubmed PY - 2004/1/6/medline PY - 2003/8/2/entrez SP - 170 EP - 5 JF - Annals of neurology JO - Ann Neurol VL - 54 IS - 2 N2 - Cigarette smoking and caffeine consumption are associated with a decreased incidence of Parkinson's disease (PD). This inverse association may result from neuroprotective effects of cigarette smoke and caffeine, or from a disinclination of future PD patients to engage in habituating behaviors. We investigated the association between consumption of alcoholic beverages, another potentially habituating behavior, and risk of PD in two large prospective cohorts Nurses' Health Study, and Health Professionals' Follow-up Study. We detected 415 new cases of PD during follow-up. Compared with nondrinkers at baseline, the relative rate (95% confidence interval) was 1.0 (0.8-1.3) for drinkers of less than 5 gm/day, 1.0 (0.8-1.4) for 5 to less than 15 gm/day, 1.1 (0.8-1.6) for 15 to less than 30 gm/day, and 0.7 (0.5-1.2) for 30 gm/day or more (p for trend = 0.45). Consumption of wine or liquor was not associated with the incidence of PD. Compared with those who consumed beer less than once per month, the relative rate (95% confidence interval) was 0.7 (0.5-0.9) for one to three drinks of beer per month, and 0.7 (0.5, 0.9) for one or more drinks of beer per week. The risk of PD was similar in individuals who usually consume moderate amounts of alcohol and in abstainers. SN - 0364-5134 UR - https://www.unboundmedicine.com/medline/citation/12891669/Alcohol_consumption_and_the_incidence_of_Parkinson's_disease_ L2 - https://doi.org/10.1002/ana.10611 DB - PRIME DP - Unbound Medicine ER -