TY - JOUR T1 - [Chronic venous insufficiency: an open trial of FLEBS Crema]. A1 - Consoli,A, PY - 2003/8/6/pubmed PY - 2004/1/24/medline PY - 2003/8/6/entrez SP - 411 EP - 6 JF - Minerva cardioangiologica JO - Minerva Cardioangiol VL - 51 IS - 4 N2 - AIM: This study was realized to evaluate the FLEBS CREMA tolerability and its therapeutic efficacy, in patients with functional disease linked to not complicated venous or lymphatic insufficiency. This compound acts as vasoconstrictor thanks to the vegetable extract of Ruscus aculeatus, but it is also able to reduce the edema, thanks to the vegetable extract of Melilotus officinalis. METHODS: All the patients were treated for three weeks with FLEBS CREMA, that was applied 2 or 3 times a day, on both legs. The traditional clinical parameters of chronic venous insufficiency (IVC) (edema, pain, heaviness, itch, cramps and other symptoms) were evaluated during the treatment. RESULTS: The results show an improvement for all the monitored symptoms, also if the positive clinical response was different for each evaluated parameter. The best results were obtained for edema, pain, heaviness and itch: the statistical analysis shows indeed a significant difference between the beginning and the end of the treatment. In this study the dermo-cosmetic qualities and the tolerability of FLEBS CREMA were also evaluated: both these parameters obtained a positive clinical evaluation. CONCLUSIONS: Basing on these data, the final evaluation for this compound was good/very good for the 80-90% both doctor and patients. SN - 0026-4725 UR - https://www.unboundmedicine.com/medline/citation/12900723/[Chronic_venous_insufficiency:_an_open_trial_of_FLEBS_Crema]_ L2 - https://medlineplus.gov/herbalmedicine.html DB - PRIME DP - Unbound Medicine ER -