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The diagnosis and treatment of gastrinoma: report of 17 cases.
Chin Med Sci J. 1999 Sep; 14(3):185-8.CM

Abstract

OBJECTIVE

To study the experience of diagnosis and treatment of gastrinoma.

METHODS

A retrospective study of 17 patients with gastrinoma seen from 1978 through 1998 in PUMC hospital.

RESULTS

Three of the 17 cases were associated with multiple endocrine neoplasia type I (MEN-I) syndrome. Tumors dispersed extensively in pancreas (31%), duodenum (25%), lymphnode (19%) and other place (25%). Ultrasonography and computed tomography (CT) were sensitive in localizing tumor in pancreas and liver, but were not so well for small tumor in duodenum and lymph node. The angiography, percutaneous transhepatic portal sampling (PTPS), scintigraphy and endoscopic ultrasonography (EUS) also can be used. Sixteen of 17 patients underwent 38 operations and 56 percent of the 16 cases underwent several operations. Seven patients at last performed total gastrectomy that was still considered as a choice of treatment. Tumor resection was rare because the advancing of tumor in most cases.

CONCLUSIONS

Diagnosing gastrinoma in its early stage and striving for the tumor resection and reducing the metastasis of liver were the cruxes for good prognosis.

Authors+Show Affiliations

Department of Surgery, PUMC Hospital, CAMS & PUMC, Beijing 100730.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12903824

Citation

Zhang, T, et al. "The Diagnosis and Treatment of Gastrinoma: Report of 17 Cases." Chinese Medical Sciences Journal = Chung-kuo I Hsueh K'o Hsueh Tsa Chih, vol. 14, no. 3, 1999, pp. 185-8.
Zhang T, Zhao Y, Xu X, et al. The diagnosis and treatment of gastrinoma: report of 17 cases. Chin Med Sci J. 1999;14(3):185-8.
Zhang, T., Zhao, Y., Xu, X., Yang, B., Cai, L., & Zhu, Y. (1999). The diagnosis and treatment of gastrinoma: report of 17 cases. Chinese Medical Sciences Journal = Chung-kuo I Hsueh K'o Hsueh Tsa Chih, 14(3), 185-8.
Zhang T, et al. The Diagnosis and Treatment of Gastrinoma: Report of 17 Cases. Chin Med Sci J. 1999;14(3):185-8. PubMed PMID: 12903824.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The diagnosis and treatment of gastrinoma: report of 17 cases. AU - Zhang,T, AU - Zhao,Y, AU - Xu,X, AU - Yang,B, AU - Cai,L, AU - Zhu,Y, PY - 2003/8/9/pubmed PY - 2003/10/18/medline PY - 2003/8/9/entrez SP - 185 EP - 8 JF - Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih JO - Chin Med Sci J VL - 14 IS - 3 N2 - OBJECTIVE: To study the experience of diagnosis and treatment of gastrinoma. METHODS: A retrospective study of 17 patients with gastrinoma seen from 1978 through 1998 in PUMC hospital. RESULTS: Three of the 17 cases were associated with multiple endocrine neoplasia type I (MEN-I) syndrome. Tumors dispersed extensively in pancreas (31%), duodenum (25%), lymphnode (19%) and other place (25%). Ultrasonography and computed tomography (CT) were sensitive in localizing tumor in pancreas and liver, but were not so well for small tumor in duodenum and lymph node. The angiography, percutaneous transhepatic portal sampling (PTPS), scintigraphy and endoscopic ultrasonography (EUS) also can be used. Sixteen of 17 patients underwent 38 operations and 56 percent of the 16 cases underwent several operations. Seven patients at last performed total gastrectomy that was still considered as a choice of treatment. Tumor resection was rare because the advancing of tumor in most cases. CONCLUSIONS: Diagnosing gastrinoma in its early stage and striving for the tumor resection and reducing the metastasis of liver were the cruxes for good prognosis. SN - 1001-9294 UR - https://www.unboundmedicine.com/medline/citation/12903824/The_diagnosis_and_treatment_of_gastrinoma:_report_of_17_cases_ L2 - https://medlineplus.gov/pancreaticcancer.html DB - PRIME DP - Unbound Medicine ER -