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[Relationship between body composition and bone mineral density in healthy premenopausal women].

Abstract

OBJECTIVE

To investigate the relative contribution of fat mass and lean mass on bone mineral density (BMD) in premenopausal healthy women.

METHODS

The BMD at lumbar spine, proximal femur and total body, together with fat mass and lean mass was determined by dual-energy X-ray absorptiometry (DEXA), the body height, weight, waist, and hip circumference were also measured, and body mass index (BMI) and waist-hip ratio were calculated in 282 premenopausal women.

RESULTS

Fat mass was a major determinant for BMI, BMI and lean mass were positively related with L2-4, proximal femur and total body BMD (P = 0.000 for all), and lean mass were the only independent factor contributing to L2-4 (standardized coefficient beta = 0.282, P = 0.000), proximal femur (beta = 0.336, P = 0.000) and total body BMD (beta = 0.361, P = 0.000) in stepwise regression analysis. The relationship between BMI and BMD was further improved after controlling fat mass, while decreased or even lost when controlling lean mass.

CONCLUSIONS

Lean mass was an important factor determining BMD in premenopausal women.

Authors+Show Affiliations

Department of Endocrinology, Rui-jin Hospital, Shanghai Second Medical University, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai 200025, China. ljmhh@public7.sta.net.cnNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

12905733

Citation

Liu, Jian-min, et al. "[Relationship Between Body Composition and Bone Mineral Density in Healthy Premenopausal Women]." Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae, vol. 25, no. 3, 2003, pp. 250-3.
Liu JM, Zhao HY, Ning G, et al. [Relationship between body composition and bone mineral density in healthy premenopausal women]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2003;25(3):250-3.
Liu, J. M., Zhao, H. Y., Ning, G., Zhang, L. Z., Xu, M. Y., & Chen, J. L. (2003). [Relationship between body composition and bone mineral density in healthy premenopausal women]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae, 25(3), pp. 250-3.
Liu JM, et al. [Relationship Between Body Composition and Bone Mineral Density in Healthy Premenopausal Women]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2003;25(3):250-3. PubMed PMID: 12905733.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Relationship between body composition and bone mineral density in healthy premenopausal women]. AU - Liu,Jian-min, AU - Zhao,Hong-yan, AU - Ning,Guang, AU - Zhang,Lian-zhen, AU - Xu,Man-yin, AU - Chen,Jia-lun, PY - 2003/8/9/pubmed PY - 2004/7/16/medline PY - 2003/8/9/entrez SP - 250 EP - 3 JF - Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae JO - Zhongguo Yi Xue Ke Xue Yuan Xue Bao VL - 25 IS - 3 N2 - OBJECTIVE: To investigate the relative contribution of fat mass and lean mass on bone mineral density (BMD) in premenopausal healthy women. METHODS: The BMD at lumbar spine, proximal femur and total body, together with fat mass and lean mass was determined by dual-energy X-ray absorptiometry (DEXA), the body height, weight, waist, and hip circumference were also measured, and body mass index (BMI) and waist-hip ratio were calculated in 282 premenopausal women. RESULTS: Fat mass was a major determinant for BMI, BMI and lean mass were positively related with L2-4, proximal femur and total body BMD (P = 0.000 for all), and lean mass were the only independent factor contributing to L2-4 (standardized coefficient beta = 0.282, P = 0.000), proximal femur (beta = 0.336, P = 0.000) and total body BMD (beta = 0.361, P = 0.000) in stepwise regression analysis. The relationship between BMI and BMD was further improved after controlling fat mass, while decreased or even lost when controlling lean mass. CONCLUSIONS: Lean mass was an important factor determining BMD in premenopausal women. SN - 1000-503X UR - https://www.unboundmedicine.com/medline/citation/12905733/[Relationship_between_body_composition_and_bone_mineral_density_in_healthy_premenopausal_women]_ L2 - https://medlineplus.gov/bonedensity.html DB - PRIME DP - Unbound Medicine ER -