Tags

Type your tag names separated by a space and hit enter

Long-chain omega-3 fatty acids from fish reduce sudden cardiac death in patients with coronary heart disease.
Eur J Med Res. 2003 Aug 20; 8(8):332-6.EJ

Abstract

An increase in the uptake of long-chain Omega-3 fatty acids from fish with the diet or as ethyl esters resulted in a decreased risk for cardiac death. As mechanism for this rapidly occurring benefit (within 90 days of treatment significantly different to placebo) antiarrhythmic effects at cardiac myocytes and plaques stabilization can be discussed. The results of the GISSI Prevenzione Trial show that 175 patients have to be treated for one year to avoid one death. Regarding other available data for secondary prevention this efficacy is superior to pravastatin and at the same level as simvastatin or aspirin. Only beta-blocking agents are superior, but it is of interest that long-chain Omega-3 fatty acids from fish display their beneficial effects even in patients already treated with beta-blockers. As the intake of 0.85 g of long-chain Omega-3 fatty acids from fish per day can be regarded as save and the positive effect on total mortality occurs already after 90 days their regular use is a promising additional measure for secondary prevention.

Authors+Show Affiliations

Institut für Fettstoffwechsel und Hämorheologie, Blumenstr. 6, D-86949 Windach, Germany. IFH-richter@t-online.de

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

12915328

Citation

Richter, W O.. "Long-chain Omega-3 Fatty Acids From Fish Reduce Sudden Cardiac Death in Patients With Coronary Heart Disease." European Journal of Medical Research, vol. 8, no. 8, 2003, pp. 332-6.
Richter WO. Long-chain omega-3 fatty acids from fish reduce sudden cardiac death in patients with coronary heart disease. Eur J Med Res. 2003;8(8):332-6.
Richter, W. O. (2003). Long-chain omega-3 fatty acids from fish reduce sudden cardiac death in patients with coronary heart disease. European Journal of Medical Research, 8(8), 332-6.
Richter WO. Long-chain Omega-3 Fatty Acids From Fish Reduce Sudden Cardiac Death in Patients With Coronary Heart Disease. Eur J Med Res. 2003 Aug 20;8(8):332-6. PubMed PMID: 12915328.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-chain omega-3 fatty acids from fish reduce sudden cardiac death in patients with coronary heart disease. A1 - Richter,W O, PY - 2003/8/14/pubmed PY - 2004/3/25/medline PY - 2003/8/14/entrez SP - 332 EP - 6 JF - European journal of medical research JO - Eur. J. Med. Res. VL - 8 IS - 8 N2 - An increase in the uptake of long-chain Omega-3 fatty acids from fish with the diet or as ethyl esters resulted in a decreased risk for cardiac death. As mechanism for this rapidly occurring benefit (within 90 days of treatment significantly different to placebo) antiarrhythmic effects at cardiac myocytes and plaques stabilization can be discussed. The results of the GISSI Prevenzione Trial show that 175 patients have to be treated for one year to avoid one death. Regarding other available data for secondary prevention this efficacy is superior to pravastatin and at the same level as simvastatin or aspirin. Only beta-blocking agents are superior, but it is of interest that long-chain Omega-3 fatty acids from fish display their beneficial effects even in patients already treated with beta-blockers. As the intake of 0.85 g of long-chain Omega-3 fatty acids from fish per day can be regarded as save and the positive effect on total mortality occurs already after 90 days their regular use is a promising additional measure for secondary prevention. SN - 0949-2321 UR - https://www.unboundmedicine.com/medline/citation/12915328/Long_chain_omega_3_fatty_acids_from_fish_reduce_sudden_cardiac_death_in_patients_with_coronary_heart_disease_ L2 - http://www.diseaseinfosearch.org/result/130 DB - PRIME DP - Unbound Medicine ER -