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Health-related quality of life in obese outpatients losing weight with very-low-energy diet and behaviour modification: a 2-y follow-up study.
Int J Obes Relat Metab Disord. 2003 Sep; 27(9):1072-80.IJ

Abstract

OBJECTIVE

To study health-related quality of life (HRQL) in a clinically selected sample obese outpatients.

DESIGN

A single-strand before and after study with 2-y follow-up after treatment comprising 10 weeks on very-low-energy diet (VLED) and 4 months of behaviour modification in groups.

SUBJECTS

A total of 126 patients (mean (s.d.) age 48.2 (11.1) y and body mass index (BMI) 42.8 (6.2) kg/m(2) (63% women)) referred for treatment in an obesity clinic.

MEASUREMENTS

Weight and HRQL using questionnaires (RAND 36-Item Health Survey 1.0 and Obesity-related Psychosocial problems-scale).

RESULTS

In all, 100 patients (61% women) completed the treatment and 67 (71% women) completed the 2-y follow-up. The mean (s.d.) weight loss was 12.5 (5.6)% at the end of group therapy, 6.0 (7.1)% at 1 y, and 2.6 (7.5)% at 2 y. At baseline, the mean (s.d.) score for OP-scale was 61.9 (24.6). The mean scores on every RAND-36 scale were markedly lower than in the Finns without chronic conditions. All the scales in HRQL improved markedly during the treatment. During the follow-up, all the scales started to return back towards baseline levels and at 2 y, only obesity-related psychosocial problems and physical functioning were still improved relative to baseline. In categories of weight change at 2 y (> or =10% weight loss, 0-9.9% weight loss, weight gain), obesity-related psychosocial functioning, physical functioning, and general health showed dose-response improvement with increasing weight loss. A > or =10% weight loss at 2 y after treatment was associated with clear improvement in obesity-related psychosocial problems, physical functioning, physical role functioning, bodily pain, general health, mental health, and vitality. A 0-9.9% weight loss was associated with improvement in obesity-related psychosocial problems and physical functioning. Weight gain was associated with improvement in obesity-related psychosocial problems and social functioning. The study population was too small to examine possible gender differences.

CONCLUSIONS

Treatment with VLED and behaviour modification produces marked short-term weight loss and clear improvement in all aspects of HRQL. At 2 y after treatment, the average maintained weight loss is modest. However, one-third of patients maintain > or =5% weight loss. Improvement in obesity-related psychosocial problems and physical functioning is associated even with &<10% of maintained weight loss. Since the pattern of HRQL changes did only partly follow the pattern of weight change as expected, other factors, such as the therapeutic effect of participating in the weight loss programme or increase in physical activity, may affect HRQL responses.

Authors+Show Affiliations

Kaukua J
Helsinki University Central Hospital, Peijas Hospital, Department of Internal Medicine, Vantaa, Finland. Jarmo.Kaukua@dlc.fi
Pekkarinen T
No affiliation info available
Sane T
No affiliation info available
Mustajoki P
No affiliation info available

MeSH

AdultBehavior TherapyChronic DiseaseEnergy IntakeFemaleFollow-Up StudiesHumansMaleMiddle AgedObesityOutpatientsPatient DropoutsPsychology, SocialQuality of LifeTime FactorsWeight Loss

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12917713

Citation

Kaukua, J, et al. "Health-related Quality of Life in Obese Outpatients Losing Weight With Very-low-energy Diet and Behaviour Modification: a 2-y Follow-up Study." International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity, vol. 27, no. 9, 2003, pp. 1072-80.
Kaukua J, Pekkarinen T, Sane T, et al. Health-related quality of life in obese outpatients losing weight with very-low-energy diet and behaviour modification: a 2-y follow-up study. Int J Obes Relat Metab Disord. 2003;27(9):1072-80.
Kaukua, J., Pekkarinen, T., Sane, T., & Mustajoki, P. (2003). Health-related quality of life in obese outpatients losing weight with very-low-energy diet and behaviour modification: a 2-y follow-up study. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity, 27(9), 1072-80.
Kaukua J, et al. Health-related Quality of Life in Obese Outpatients Losing Weight With Very-low-energy Diet and Behaviour Modification: a 2-y Follow-up Study. Int J Obes Relat Metab Disord. 2003;27(9):1072-80. PubMed PMID: 12917713.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Health-related quality of life in obese outpatients losing weight with very-low-energy diet and behaviour modification: a 2-y follow-up study. AU - Kaukua,J, AU - Pekkarinen,T, AU - Sane,T, AU - Mustajoki,P, PY - 2003/8/15/pubmed PY - 2003/10/21/medline PY - 2003/8/15/entrez SP - 1072 EP - 80 JF - International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity JO - Int J Obes Relat Metab Disord VL - 27 IS - 9 N2 - OBJECTIVE: To study health-related quality of life (HRQL) in a clinically selected sample obese outpatients. DESIGN: A single-strand before and after study with 2-y follow-up after treatment comprising 10 weeks on very-low-energy diet (VLED) and 4 months of behaviour modification in groups. SUBJECTS: A total of 126 patients (mean (s.d.) age 48.2 (11.1) y and body mass index (BMI) 42.8 (6.2) kg/m(2) (63% women)) referred for treatment in an obesity clinic. MEASUREMENTS: Weight and HRQL using questionnaires (RAND 36-Item Health Survey 1.0 and Obesity-related Psychosocial problems-scale). RESULTS: In all, 100 patients (61% women) completed the treatment and 67 (71% women) completed the 2-y follow-up. The mean (s.d.) weight loss was 12.5 (5.6)% at the end of group therapy, 6.0 (7.1)% at 1 y, and 2.6 (7.5)% at 2 y. At baseline, the mean (s.d.) score for OP-scale was 61.9 (24.6). The mean scores on every RAND-36 scale were markedly lower than in the Finns without chronic conditions. All the scales in HRQL improved markedly during the treatment. During the follow-up, all the scales started to return back towards baseline levels and at 2 y, only obesity-related psychosocial problems and physical functioning were still improved relative to baseline. In categories of weight change at 2 y (> or =10% weight loss, 0-9.9% weight loss, weight gain), obesity-related psychosocial functioning, physical functioning, and general health showed dose-response improvement with increasing weight loss. A > or =10% weight loss at 2 y after treatment was associated with clear improvement in obesity-related psychosocial problems, physical functioning, physical role functioning, bodily pain, general health, mental health, and vitality. A 0-9.9% weight loss was associated with improvement in obesity-related psychosocial problems and physical functioning. Weight gain was associated with improvement in obesity-related psychosocial problems and social functioning. The study population was too small to examine possible gender differences. CONCLUSIONS: Treatment with VLED and behaviour modification produces marked short-term weight loss and clear improvement in all aspects of HRQL. At 2 y after treatment, the average maintained weight loss is modest. However, one-third of patients maintain > or =5% weight loss. Improvement in obesity-related psychosocial problems and physical functioning is associated even with &<10% of maintained weight loss. Since the pattern of HRQL changes did only partly follow the pattern of weight change as expected, other factors, such as the therapeutic effect of participating in the weight loss programme or increase in physical activity, may affect HRQL responses. UR - https://www.unboundmedicine.com/medline/citation/12917713/Health_related_quality_of_life_in_obese_outpatients_losing_weight_with_very_low_energy_diet_and_behaviour_modification:_a_2_y_follow_up_study_ DB - PRIME DP - Unbound Medicine ER -