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Outcome of symptomatic patients undergoing extracardiac Fontan conversion and cryoablation.
J Thorac Cardiovasc Surg. 2003 Aug; 126(2):529-36.JT

Abstract

OBJECTIVE

We review our experience with Fontan conversion and cryoablation in patients with an atriopulmonary Fontan in low cardiac output from arrhythmia or venous obstruction, including 2 patients with protein-losing enteropathy.

METHODS

Ten patients (mean age 21.1 +/- 7.0 years) underwent extracardiac Fontan conversion, cryoablation, and pacemaker placement between November 1999 and April 2002 (13.1 +/- 4.1 years after the original atriopulmonary connection). Eight patients were in New York Heart Association class III and 2 were in New York Heart Association class IV. Nine patients had clinically important intra-atrial reentry tachycardia refractory to medical therapy.

RESULTS

Follow-up was between 3.1 and 32.6 months (16.8 +/- 9). One death occurred at 7 days after surgery due to sepsis and multisystem organ failure. The second death occurred at 48 days from complications of protein-losing enteropathy. The second patient with protein-losing enteropathy had improved New York Heart Association classification, cessation of albumin transfusions, and a normal stool alpha antitrypsin level (down from 4.1 mg/g preoperatively). Five patients improved to New York Heart Association class I and 3 patients to New York Heart Association class II. Sustained arrhythmias could not be induced in any patient. Seven patients are on no antiarrhythmics. One patient had recurrence of intra-atrial reentrant tachycardia 11 months postoperatively, which required electrical cardioversion; this patient's symptoms are currently well controlled on 1 medication.

CONCLUSION

Extracardiac Fontan, cryoablation, and pacemaker placement reduced atrial arrhythmias and improved New York Heart Association classification in all surviving patients. In selected patients, this operation offers improvement in clinical outcome and is an alternative to transplantation. Protein-losing enteropathy may not be a contraindication to performing Fontan conversion with cryoablation.

Authors+Show Affiliations

Division of Pediatric Cardiothoracic Surgery, Children's HospitalColumbus, Education Building-Room 642, 700 Children's Drive, Columbus, OH 43205, USA. Weinstes@chi.osu.eduNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12928654

Citation

Weinstein, Samuel, et al. "Outcome of Symptomatic Patients Undergoing Extracardiac Fontan Conversion and Cryoablation." The Journal of Thoracic and Cardiovascular Surgery, vol. 126, no. 2, 2003, pp. 529-36.
Weinstein S, Cua C, Chan D, et al. Outcome of symptomatic patients undergoing extracardiac Fontan conversion and cryoablation. J Thorac Cardiovasc Surg. 2003;126(2):529-36.
Weinstein, S., Cua, C., Chan, D., & Davis, J. T. (2003). Outcome of symptomatic patients undergoing extracardiac Fontan conversion and cryoablation. The Journal of Thoracic and Cardiovascular Surgery, 126(2), 529-36.
Weinstein S, et al. Outcome of Symptomatic Patients Undergoing Extracardiac Fontan Conversion and Cryoablation. J Thorac Cardiovasc Surg. 2003;126(2):529-36. PubMed PMID: 12928654.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outcome of symptomatic patients undergoing extracardiac Fontan conversion and cryoablation. AU - Weinstein,Samuel, AU - Cua,Cliff, AU - Chan,David, AU - Davis,J Terrance, PY - 2003/8/21/pubmed PY - 2003/10/30/medline PY - 2003/8/21/entrez SP - 529 EP - 36 JF - The Journal of thoracic and cardiovascular surgery JO - J Thorac Cardiovasc Surg VL - 126 IS - 2 N2 - OBJECTIVE: We review our experience with Fontan conversion and cryoablation in patients with an atriopulmonary Fontan in low cardiac output from arrhythmia or venous obstruction, including 2 patients with protein-losing enteropathy. METHODS: Ten patients (mean age 21.1 +/- 7.0 years) underwent extracardiac Fontan conversion, cryoablation, and pacemaker placement between November 1999 and April 2002 (13.1 +/- 4.1 years after the original atriopulmonary connection). Eight patients were in New York Heart Association class III and 2 were in New York Heart Association class IV. Nine patients had clinically important intra-atrial reentry tachycardia refractory to medical therapy. RESULTS: Follow-up was between 3.1 and 32.6 months (16.8 +/- 9). One death occurred at 7 days after surgery due to sepsis and multisystem organ failure. The second death occurred at 48 days from complications of protein-losing enteropathy. The second patient with protein-losing enteropathy had improved New York Heart Association classification, cessation of albumin transfusions, and a normal stool alpha antitrypsin level (down from 4.1 mg/g preoperatively). Five patients improved to New York Heart Association class I and 3 patients to New York Heart Association class II. Sustained arrhythmias could not be induced in any patient. Seven patients are on no antiarrhythmics. One patient had recurrence of intra-atrial reentrant tachycardia 11 months postoperatively, which required electrical cardioversion; this patient's symptoms are currently well controlled on 1 medication. CONCLUSION: Extracardiac Fontan, cryoablation, and pacemaker placement reduced atrial arrhythmias and improved New York Heart Association classification in all surviving patients. In selected patients, this operation offers improvement in clinical outcome and is an alternative to transplantation. Protein-losing enteropathy may not be a contraindication to performing Fontan conversion with cryoablation. SN - 0022-5223 UR - https://www.unboundmedicine.com/medline/citation/12928654/Outcome_of_symptomatic_patients_undergoing_extracardiac_Fontan_conversion_and_cryoablation_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022522303002125 DB - PRIME DP - Unbound Medicine ER -