Tags

Type your tag names separated by a space and hit enter

The efficacy of treatment with intralesional meglumine antimoniate alone, compared with that of cryotherapy combined with the meglumine antimoniate or intralesional sodium stibogluconate, in the treatment of cutaneous leishmaniasis.
Ann Trop Med Parasitol. 2003 Jul; 97(5):493-8.AT

Abstract

It would be very useful to have a more effective and more rapid method available for the treatment of cutaneous leishmaniasis (CL). The main aim of the present, Iranian study, was to see if the combination of cryotherapy and intralesional injections with meglumine antimoniate (C + MA) would be more effective than the injections given alone (MA) or the combination of cryotherapy plus intralesional sodium stibogluconate (C + SS). Forty patients (with 67 lesions) were treated with C + MA, another 40 (with 65 lesions) were treated with C + SS and 100 patients (with 180 lesions) were treated with MA. Follow-up for 6 months after the final treatment indicated that 89.5% of the lesions treated with C + MA, 92.3% of those treated with C + SS but only 50% of the lesions treated with MA only were completely cured. The frequencies of cure in the two cryotherapy groups were similar, both being significantly higher than that in the MA group (P < 0.05). The combination of cryotherapy with intralesional injections of meglumine antimoniate or sodium stibogluconate, which is much more effective than the use of intralesional meglumine antimoniate alone, should be promoted.

Authors+Show Affiliations

Department of Dermatology, St Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12930612

Citation

Asilian, A, et al. "The Efficacy of Treatment With Intralesional Meglumine Antimoniate Alone, Compared With That of Cryotherapy Combined With the Meglumine Antimoniate or Intralesional Sodium Stibogluconate, in the Treatment of Cutaneous Leishmaniasis." Annals of Tropical Medicine and Parasitology, vol. 97, no. 5, 2003, pp. 493-8.
Asilian A, Sadeghinia A, Faghihi G, et al. The efficacy of treatment with intralesional meglumine antimoniate alone, compared with that of cryotherapy combined with the meglumine antimoniate or intralesional sodium stibogluconate, in the treatment of cutaneous leishmaniasis. Ann Trop Med Parasitol. 2003;97(5):493-8.
Asilian, A., Sadeghinia, A., Faghihi, G., Momeni, A., & Amini Harandi, A. (2003). The efficacy of treatment with intralesional meglumine antimoniate alone, compared with that of cryotherapy combined with the meglumine antimoniate or intralesional sodium stibogluconate, in the treatment of cutaneous leishmaniasis. Annals of Tropical Medicine and Parasitology, 97(5), 493-8.
Asilian A, et al. The Efficacy of Treatment With Intralesional Meglumine Antimoniate Alone, Compared With That of Cryotherapy Combined With the Meglumine Antimoniate or Intralesional Sodium Stibogluconate, in the Treatment of Cutaneous Leishmaniasis. Ann Trop Med Parasitol. 2003;97(5):493-8. PubMed PMID: 12930612.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The efficacy of treatment with intralesional meglumine antimoniate alone, compared with that of cryotherapy combined with the meglumine antimoniate or intralesional sodium stibogluconate, in the treatment of cutaneous leishmaniasis. AU - Asilian,A, AU - Sadeghinia,A, AU - Faghihi,G, AU - Momeni,A, AU - Amini Harandi,A, PY - 2003/8/22/pubmed PY - 2003/10/8/medline PY - 2003/8/22/entrez SP - 493 EP - 8 JF - Annals of tropical medicine and parasitology JO - Ann Trop Med Parasitol VL - 97 IS - 5 N2 - It would be very useful to have a more effective and more rapid method available for the treatment of cutaneous leishmaniasis (CL). The main aim of the present, Iranian study, was to see if the combination of cryotherapy and intralesional injections with meglumine antimoniate (C + MA) would be more effective than the injections given alone (MA) or the combination of cryotherapy plus intralesional sodium stibogluconate (C + SS). Forty patients (with 67 lesions) were treated with C + MA, another 40 (with 65 lesions) were treated with C + SS and 100 patients (with 180 lesions) were treated with MA. Follow-up for 6 months after the final treatment indicated that 89.5% of the lesions treated with C + MA, 92.3% of those treated with C + SS but only 50% of the lesions treated with MA only were completely cured. The frequencies of cure in the two cryotherapy groups were similar, both being significantly higher than that in the MA group (P < 0.05). The combination of cryotherapy with intralesional injections of meglumine antimoniate or sodium stibogluconate, which is much more effective than the use of intralesional meglumine antimoniate alone, should be promoted. SN - 0003-4983 UR - https://www.unboundmedicine.com/medline/citation/12930612/The_efficacy_of_treatment_with_intralesional_meglumine_antimoniate_alone_compared_with_that_of_cryotherapy_combined_with_the_meglumine_antimoniate_or_intralesional_sodium_stibogluconate_in_the_treatment_of_cutaneous_leishmaniasis_ L2 - https://www.diseaseinfosearch.org/result/4166 DB - PRIME DP - Unbound Medicine ER -